Gene Symbol | DPF1 |
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Entrez Gene | 8193 |
Alt Symbol | BAF45b, NEUD4, neuro-d4 |
Species | Human |
Gene Type | protein-coding |
Description | D4, zinc and double PHD fingers family 1 |
Other Description | BRG1-associated factor 45B|neuro-d4 homolog|zinc finger protein neuro-d4 |
Swissprots | Q08AJ0 B3KSY8 Q92782 |
Accessions | EAW56760 EAW56761 EAW56762 EAW56763 Q92782 AI857563 AI885717 AK094632 BAG52900 AK127198 AK297581 BAG59970 AK308563 AL529673 AL538568 BC021191 AAH21191 BC125152 AAI25153 BC125153 AAI25154 GQ358728 ACU65923 U43843 AAC50685 XM_005259289 XP_005259346 XM_005259290 XP_005259347 XM_005259292 XP_005259349 XM_006723407 XP_006723470 XM_006723408 XP_006723471 XM_006723409 XP_006723472 XM_006723410 XP_006723473 XM_011527356 XP_011525658 XM_011527357 XP_011525659 XM_011527358 XP_011525660 XR_243964 NM_001135155 NP_001128627 NM_001135156 NP_001128628 NM_001289978 NP_001276907 NM_004647 NP_004638 |
Function | May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regula |
Subcellular Location | Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}. |
DPF1 (E-12) - sc-132660 from Santa Cruz Biotechnology
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DPF1 (N-12) - sc-132661 from Santa Cruz Biotechnology
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DPF1 (J-16) - sc-101942 from Santa Cruz Biotechnology
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Anti-Neuro D4 antibody - ab173160 from Abcam
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Anti-Neuro D4 antibody - ab3940 from Abcam
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Anti-Neuro D4 antibody - C-terminal - ab199299 from Abcam
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Anti-DPF1 / Neuro-D4 Antibody (aa402-414) - LS-C55164 from LifeSpan Bioscience
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Anti-DPF1 / Neuro-D4 Antibody (aa229-278) - LS-C29898 from LifeSpan Bioscience
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Anti-DPF1 / Neuro-D4 Antibody (aa219-247, APC) - LS-C256276 from LifeSpan Bioscience
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Anti-DPF1 / Neuro-D4 Antibody (aa219-247, FITC) - LS-C256278 from LifeSpan Bioscience
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Anti-DPF1 / Neuro-D4 Antibody (aa219-247, AP) - LS-C256275 from LifeSpan Bioscience
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Anti-DPF1 / Neuro-D4 Antibody (aa219-247, Biotin) - LS-C256277 from LifeSpan Bioscience
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Anti-DPF1 / Neuro-D4 Antibody (aa219-247, Azide-free, HRP) - LS-C256280 from LifeSpan Bioscience
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Anti-DPF1 / Neuro-D4 Antibody (aa219-247, PE) - LS-C256279 from LifeSpan Bioscience
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Anti-DPF1 / Neuro-D4 Antibody (aa219-247) - LS-C320936 from LifeSpan Bioscience
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Anti-DPF1 / Neuro-D4 Antibody (aa220-247) - LS-C159484 from LifeSpan Bioscience
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Neuro D4 Antibody - NBP2-13932 from Novus Biologicals
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Neuro D4 Antibody - NBP1-80040 from Novus Biologicals
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Neuro D4 Antibody - NBP2-19518 from Novus Biologicals
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Neuro D4/DPF1 Polyclonal Antibody - bs-11573R from Bioss
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Rabbit Anti-Neuro D4/DPF1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11573R-A350 from Bioss
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Rabbit Anti-Neuro D4/DPF1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11573R-A488 from Bioss
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Rabbit Anti-Neuro D4/DPF1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11573R-A555 from Bioss
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Rabbit Anti-Neuro D4/DPF1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11573R-A647 from Bioss
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Rabbit Anti-Neuro D4/DPF1 Polyclonal Antibody, Cy3 Conjugated - bs-11573R-Cy3 from Bioss
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