Gene Symbol | DPF1 |
---|---|
Entrez Gene | 8193 |
Alt Symbol | BAF45b, NEUD4, neuro-d4 |
Species | Human |
Gene Type | protein-coding |
Description | D4, zinc and double PHD fingers family 1 |
Other Description | BRG1-associated factor 45B|neuro-d4 homolog|zinc finger protein neuro-d4 |
Swissprots | Q08AJ0 B3KSY8 Q92782 |
Accessions | EAW56760 EAW56761 EAW56762 EAW56763 Q92782 AI857563 AI885717 AK094632 BAG52900 AK127198 AK297581 BAG59970 AK308563 AL529673 AL538568 BC021191 AAH21191 BC125152 AAI25153 BC125153 AAI25154 GQ358728 ACU65923 U43843 AAC50685 XM_005259289 XP_005259346 XM_005259290 XP_005259347 XM_005259292 XP_005259349 XM_006723407 XP_006723470 XM_006723408 XP_006723471 XM_006723409 XP_006723472 XM_006723410 XP_006723473 XM_011527356 XP_011525658 XM_011527357 XP_011525659 XM_011527358 XP_011525660 XR_243964 NM_001135155 NP_001128627 NM_001135156 NP_001128628 NM_001289978 NP_001276907 NM_004647 NP_004638 |
Function | May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regula |
Subcellular Location | Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}. |
DPF1 - MBS1276454 from MyBioSource
|
||||||||
Human DPF1 cDNA clone(NM_001135155.1) - CDFH005370 from Creative Biomart
|
||||||||
Human DPF1 cDNA clone(NM_001135156.1) - CDFH005371 from Creative Biomart
|
||||||||
Human DPF1 cDNA clone(NM_004647.2) - CDFH005373 from Creative Biomart
|
||||||||
Human DPF1 ORF Clone(NM_004647.2) - CDCL161447 from Creative Biomart
|
||||||||
Human DPF1 ORF Clone(NM_004647.2) - CDCR288539 from Creative Biomart
|
||||||||
Human DPF1 ORF Clone(NM_004647.2) - CDCR288541 from Creative Biomart
|
||||||||
Human DPF1 ORF Clone(NM_001135155.1) - CDCR350252 from Creative Biomart
|
||||||||
Human DPF1 ORF Clone(NM_001135156.1) - CDCR350253 from Creative Biomart
|
||||||||
Human DPF1 ORF Clone(NM_001135156.1) - CDCR350254 from Creative Biomart
|
||||||||
Human DPF1 ORF Clone(NM_001135155.1) - CDCR350258 from Creative Biomart
|
||||||||
Human DPF1 ORF clone (NM_001135156.1) - CDCR057028 from Creative biogene
|
||||||||
Human DPF1 ORF clone (NM_001135155.1) - CDCR057030 from Creative biogene
|
||||||||
Human DPF1 ORF clone (NM_004647.2) - CDCR057032 from Creative biogene
|
||||||||
Human DPF1 ORF Clone (BC125153) - CDCS411891 from Creative biogene
|
||||||||
Human DPF1 cDNA Clone(NM_001135155.1) - CDFH005370 from Creative biogene
|
||||||||
Human DPF1 cDNA Clone(NM_001135156.1) - CDFH005371 from Creative biogene
|
||||||||
Human DPF1 cDNA Clone(NM_004647.2) - CDFH005373 from Creative biogene
|
||||||||