CD244

Gene Symbol	CD244
Entrez Gene	51744
Alt Symbol	2B4, NAIL, NKR2B4, Nmrk, SLAMF4
Species	Human
Gene Type	protein-coding
Description	CD244 molecule, natural killer cell receptor 2B4
Other Description	NK cell activation inducing ligand NAIL\|NK cell activation-inducing ligand\|NK cell type I receptor protein 2B4\|SLAM family member 4\|h2B4\|natural killer cell receptor 2B4\|signaling lymphocytic activation molecule 4
Swissprots	Q9Y288 Q5VYI2 Q5VYI6 Q5VYI7 Q96T47 Q9BZW8 Q9NQD2 Q9NQD3
Accessions	AAK57926 CAJ33698 EAW52691 EAW52692 EAW52693 EAW52694 Q9BZW8 AF105261 AAD32538 AF107761 AAD37838 AF117711 AAF28833 AF145782 AAD38951 AF242540 AAK00233 AF363452 AAK50015 AJ245375 CAC00647 AJ245376 CAC00648 AJ245377 CAC00649 AK295950 BAG58732 AK313201 BAG36017 BC028073 AAH28073 BC041607 BC053985 AAH53985 HQ448452 ADQ32932 XM_011509620 XP_011507922 XM_011509621 XP_011507923 XM_011509622 XP_011507924 XM_011509623 XP_011507925 NM_001166663 NP_001160135 NM_001166664 NP_001160136 NM_016382 NP_057466
Function	Modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family. {ECO:0000269\|PubMed:10359122}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils. {ECO:0000269\|PubMed:10556801}.
Top Pathways	Natural killer cell mediated cytotoxicity

NK 2B4 (T-20) - sc-18165 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

NK 2B4 (T-20): sc-18165. Western blot analysis of NK 2B4 expression in Ramos whole cell lysate.

NK 2B4 (HD2) - sc-53596 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

NK 2B4 (HD2): sc-53596. Western blot analysis of NK 2B4 expression in non-transfected: sc-117752 (A) and human NK 2B4 transfected: sc-117189 (B) 293T whole cell lysates.

NK 2B4 (2B4.69) - sc-80900 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

NK 2B4 (M-20) - sc-18167 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

NK 2B4 (M-20): sc-18167. Western blot analysis of NK 2B4 expression in Ramos whole cell lysate.

Anti-CD244 antibody - ab113289 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Lane 1 : Anti-CD244 antibody (ab113289) at 1 µg/mlLane 2 : Anti-CD244 antibody (ab113289) at 2 µg/mlLane 1 : Daudi cell lysateLane 2 : Daudi cell lysateLysates/proteins at 15 µg per lane.

Anti-CD244 antibody - ab196745 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-CD244 antibody (ab196745) at 1/500 dilutionLane 1 : Jurkat cell extractLane 2 : H460 cell extractLane 3 : 293T cell extractLane 4 : Mouse spleen extract

Anti-CD244 antibody - ab102667 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CD244 antibody (ab102667) at 1/500 dilution + Mouse Liver Tissue Lysate at 50 µg

Anti-CD244 antibody - ab99455 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

All lanes : Anti-CD244 antibody (ab99455) at 2 µg/mlLane 1 : IP from a lysate of Human Natural Killer cells with pervanadate treatmentLane 2 : IP from a lysate of Human Natural Killer cells without treatmentdeveloped using the ECL technique

Anti-CD244 antibody - ab40160 from Abcam

Prices	$359.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CD244 antibody [2B4.69] (Phycoerythrin) - ab42896 from Abcam

Prices	$216.00
Sizes	50 tests
Host	Mouse
Clonality	Monoclonal
Clone	2B4.69

Anti-CD244 antibody [DM244] (FITC) - ab95806 from Abcam

Prices	$165.00
Sizes	50 tests
Host	Mouse
Clonality	Monoclonal
Clone	DM244

Staining of normal human peripheral blood cells with Anti-Human CD56 PE and Mouse IgG1 ? Isotype Control FITC (left) or ab95806 (right). Total viable cells were used for analysis.

Anti-CD244 antibody [MM0070-7D24] - ab89069 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	MM0070-7D24

Anti-CD244 Antibody (aa261-271) - LS-C108903 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

CD244 antibody (2 ug/ml) staining of IP from a lysate of Human Natural Killer cells with (+) or without (-) pervanadate treatment of the cells. Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-CD244 Antibody (aa220-269) - LS-C145624 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

CD244 antibody LS-C145624 Western blot of COL0205 Cell lysate. Antibody concentration 1 ug/ml.

Anti-CD244 Antibody (aa20-221) - LS-C295550 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CD244 Antibody - LS-C331813 from LifeSpan Bioscience

Prices	$255.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of extracts of various cell lines, using CD244 antibody.

Anti-CD244 Antibody (C-Terminus) - LS-C144353 from LifeSpan Bioscience

Prices	$345.00, $1,035.00
Sizes	100 µg, 500 µg
Host	Rabbit
Clonality	Polyclonal

Immunofluorescence of SLAMF4 in Daudi cells with SLAMF4 antibody at 20 ug/ml.

Anti-CD244 Antibody (CF) - LS-C37675 from LifeSpan Bioscience

Prices	$605.00
Sizes	100 tst
Host	Goat
Clonality	Polyclonal

Anti-CD244 Antibody (Low Endotoxin) - LS-C44847 from LifeSpan Bioscience

Prices	$445.00
Sizes	500 µg
Host	Mouse
Clonality	Monoclonal

Anti-CD244 Antibody (RPE) - LS-C44849 from LifeSpan Bioscience

Prices	$350.00
Sizes	100 tst
Host	Mouse
Clonality	Monoclonal

Anti-CD244 Antibody (Extracellular Domain) - LS-C73610 from LifeSpan Bioscience

Prices	$605.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-CD244 Antibody (Extracellular Domain, CF) - LS-C73611 from LifeSpan Bioscience

Prices	$605.00
Sizes	100 tst
Host	Goat
Clonality	Polyclonal

Anti-CD244 Antibody (Extracellular Domain, Biotin) - LS-C125331 from LifeSpan Bioscience

Prices	$650.00
Sizes	50 µg
Host	Goat
Clonality	Polyclonal

Anti-CD244 Antibody (Extracellular Domain) - LS-C123189 from LifeSpan Bioscience

Prices	$605.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-CD244 Antibody (Extracellular Domain) - LS-C126039 from LifeSpan Bioscience

Prices	$575.00
Sizes	500 µg
Host	Mouse
Clonality	Monoclonal

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