CD244

Gene Symbol	CD244
Entrez Gene	51744
Alt Symbol	2B4, NAIL, NKR2B4, Nmrk, SLAMF4
Species	Human
Gene Type	protein-coding
Description	CD244 molecule, natural killer cell receptor 2B4
Other Description	NK cell activation inducing ligand NAIL|NK cell activation-inducing ligand|NK cell type I receptor protein 2B4|SLAM family member 4|h2B4|natural killer cell receptor 2B4|signaling lymphocytic activation molecule 4
Swissprots	Q9Y288 Q5VYI2 Q5VYI6 Q5VYI7 Q96T47 Q9BZW8 Q9NQD2 Q9NQD3
Accessions	AAK57926 CAJ33698 EAW52691 EAW52692 EAW52693 EAW52694 Q9BZW8 AF105261 AAD32538 AF107761 AAD37838 AF117711 AAF28833 AF145782 AAD38951 AF242540 AAK00233 AF363452 AAK50015 AJ245375 CAC00647 AJ245376 CAC00648 AJ245377 CAC00649 AK295950 BAG58732 AK313201 BAG36017 BC028073 AAH28073 BC041607 BC053985 AAH53985 HQ448452 ADQ32932 XM_011509620 XP_011507922 XM_011509621 XP_011507923 XM_011509622 XP_011507924 XM_011509623 XP_011507925 NM_001166663 NP_001160135 NM_001166664 NP_001160136 NM_016382 NP_057466
Function	Modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family. {ECO:0000269|PubMed:10359122}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils. {ECO:0000269|PubMed:10556801}.
Top Pathways	Natural killer cell mediated cytotoxicity

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human CD244 protein fragment - ab185248 from Abcam Category Protein Prices $735.00 Sizes 100 µg Source HEK 293 cells Species Human

Active human CD244 protein fragment - ab185251 from Abcam Category Protein Prices $735.00 Sizes 100 µg Source HEK 293 cells Species Human

Human CD244 protein fragment - ab130055 from Abcam Category Protein Prices $297.00 Sizes 50 µg Source E. coli Species Human

CD244 Antibody Blocking Peptide - LS-E22442 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD244 Antibody Blocking Peptide - LS-E31101 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

2B4/CD244/SLAMF4 Recombinant Protein - H00051744-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

2B4/CD244/SLAMF4 Partial Recombinant Protein - H00051744-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

2B4/CD244/SLAMF4 Blocking Peptide - NBP1-76558PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Recombinant Human 2B4/CD244/SLAMF4 Protein - NBP1-98875 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E.coli Species Human

2B4/CD244/SLAMF4 Recombinant Protein - H00051744-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

Recombinant Human 2B4/CD244/SLAMF4 Fc Chimera, CF - 1039-2B-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human 2B4 Fc tag protein - orb82848 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human CD244 protein - orb168068 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

Human 2B4 His tag protein - orb83812 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Goat anti CD244 antibody Immunizing peptide - orb15213 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

CD244 Blocking Peptide - 33R-10327 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CD244 protein (His tag) - 80R-2406 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

CD244 Peptide - AC21-0013-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CD244 (19-224, His-tag) - AR50487PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

CD244 (19-224, His-tag) - AR50487PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

CD244 - H00051744-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD244 - H00051744-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

CD244 - H00051744-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD244 - H00051744-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CD244 control peptide - AP26134CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

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