CD244

Gene Symbol CD244
Entrez Gene 51744
Alt Symbol 2B4, NAIL, NKR2B4, Nmrk, SLAMF4
Species Human
Gene Type protein-coding
Description CD244 molecule, natural killer cell receptor 2B4
Other Description NK cell activation inducing ligand NAIL|NK cell activation-inducing ligand|NK cell type I receptor protein 2B4|SLAM family member 4|h2B4|natural killer cell receptor 2B4|signaling lymphocytic activation molecule 4
Swissprots Q9Y288 Q5VYI2 Q5VYI6 Q5VYI7 Q96T47 Q9BZW8 Q9NQD2 Q9NQD3
Accessions AAK57926 CAJ33698 EAW52691 EAW52692 EAW52693 EAW52694 Q9BZW8 AF105261 AAD32538 AF107761 AAD37838 AF117711 AAF28833 AF145782 AAD38951 AF242540 AAK00233 AF363452 AAK50015 AJ245375 CAC00647 AJ245376 CAC00648 AJ245377 CAC00649 AK295950 BAG58732 AK313201 BAG36017 BC028073 AAH28073 BC041607 BC053985 AAH53985 HQ448452 ADQ32932 XM_011509620 XP_011507922 XM_011509621 XP_011507923 XM_011509622 XP_011507924 XM_011509623 XP_011507925 NM_001166663 NP_001160135 NM_001166664 NP_001160136 NM_016382 NP_057466
Function Modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family. {ECO:0000269|PubMed:10359122}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils. {ECO:0000269|PubMed:10556801}.
Top Pathways Natural killer cell mediated cytotoxicity

NK 2B4 CRISPR/Cas9 KO Plasmid (h) - sc-405266 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NK 2B4 HDR Plasmid (h) - sc-405266-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NK 2B4 Double Nickase Plasmid (h) - sc-405266-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NK 2B4 Double Nickase Plasmid (h2) - sc-405266-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NK 2B4 CRISPR Activation Plasmid (h) - sc-405266-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NK 2B4 CRISPR Activation Plasmid (h2) - sc-405266-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NK 2B4 Lentiviral Activation Particles (h) - sc-405266-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NK 2B4 Lentiviral Activation Particles (h2) - sc-405266-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NK 2B4 siRNA (h) - sc-42944 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NK 2B4 shRNA Plasmid (h) - sc-42944-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NK 2B4 shRNA (h) Lentiviral Particles - sc-42944-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

2B4/CD244/SLAMF4 RNAi - H00051744-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU069051 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5703 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5703 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08747 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08747

CD244 siRNA (Human) - CRH9929 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD244 - MBS8202845 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CD244 (NM_016382.3) - SHH258777 from Creative biogene

Category siRNA
Species Reactivities Human

Human CD244 siRNA - orb270431 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD244 shRNA Plasmid (Human) - CHH9929 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CD244 miRNA 3'UTR clone - MiUTR4H-TG01875 from Creative biogene

Species Reactivities Human
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