RNF114

Gene Symbol RNF114
Entrez Gene 55905
Alt Symbol PSORS12, ZNF313
Species Human
Gene Type protein-coding
Description ring finger protein 114
Other Description E3 ubiquitin-protein ligase RNF114|zinc finger protein 228|zinc finger protein 313
Swissprots Q9Y508 E1P627 Q6N0B0 B2RDQ9 B4DWY5
Accessions EAW75641 EAW75642 EAW75643 EAW75644 Q9Y508 AF131742 AF265215 AAF75763 AK091976 AK097265 AK297188 BAG59677 AK301731 BAG63197 AK315638 BAG38006 BC013695 AAH13695 BC066919 AAH66919 BM830132 BT006795 AAP35441 BX640603 CAE45709 HQ447087 ADQ31574 NM_018683 NP_061153
Function E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis. {ECO:0000269|PubMed:23645206}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:23645206}. Nucleus {ECO:0000269|PubMed:23645206}.
Tissue Specificity Expressed in numerous tissues, including skin, CD4 lymphocytes and dendritic cells. Highest levels in testis. {ECO:0000269|PubMed:18364390}.

RNF114-Over-expression-Lysate - LY13132a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag RNF114 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RNF114 gene.

RNF114-Over-expression-Lysate - LY10902a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag RNF114 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RNF114 gene

ZNF313 293T Cell Transient Overexpression Lysate(Denatured) - H00055905-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

RNF114 overexpression lysate - LY412984 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

RNF114 293 Cell Lysate - 406298 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

ZNF313 Overexpression Lysate (Native) - NBL1-15413 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: ZNF313 Overexpression Lysate (Adult Normal) [NBL1-15413] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ZNF313.

ZNF313 (h): 293T Lysate - sc-112985 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

RNF114 Over-expression Lysate Product - GWB-3FE5D6 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

ZNF313 Overexpression Lysate (Denatured) - H00055905-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

ZNF313 Overexpression Lysate (Denatured) - H00055905-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human RNF114 Knockdown Stable Cell Line - CSC-DC013372 from Creative biogene

Category Cell Line
Species Human
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