Gene Symbol | RNF114 |
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Entrez Gene | 55905 |
Alt Symbol | PSORS12, ZNF313 |
Species | Human |
Gene Type | protein-coding |
Description | ring finger protein 114 |
Other Description | E3 ubiquitin-protein ligase RNF114|zinc finger protein 228|zinc finger protein 313 |
Swissprots | Q9Y508 E1P627 Q6N0B0 B2RDQ9 B4DWY5 |
Accessions | EAW75641 EAW75642 EAW75643 EAW75644 Q9Y508 AF131742 AF265215 AAF75763 AK091976 AK097265 AK297188 BAG59677 AK301731 BAG63197 AK315638 BAG38006 BC013695 AAH13695 BC066919 AAH66919 BM830132 BT006795 AAP35441 BX640603 CAE45709 HQ447087 ADQ31574 NM_018683 NP_061153 |
Function | E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis. {ECO:0000269|PubMed:23645206}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:23645206}. Nucleus {ECO:0000269|PubMed:23645206}. |
Tissue Specificity | Expressed in numerous tissues, including skin, CD4 lymphocytes and dendritic cells. Highest levels in testis. {ECO:0000269|PubMed:18364390}. |
Human ZNF313 full length protein - ab177670 from Abcam
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RNF114 / ZNF313 Antibody Blocking Peptide - LS-E7935 from LifeSpan Bioscience
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RNF114 / ZNF313 Antibody Blocking Peptide - LS-E11694 from LifeSpan Bioscience
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ZNF313 Recombinant Protein - H00055905-P01 from Novus Biologicals
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ZNF313-Antibody-C-term-Blocking-peptide - BP5694b from Abgent, a WuXi AppTec company
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RNF114 protein (His tag) - 80R-3734 from Fitzgerald
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RNF114 (1-228, His-tag) - AR51421PU-N from Acris Antibodies
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RNF114 (1-228, His-tag) - AR51421PU-S from Acris Antibodies
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RNF114 - H00055905-P01-10 from Acris Antibodies
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RNF114 - H00055905-P01-25 from Acris Antibodies
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RNF114, 1-228aa Human, His tag, E.coli - 01-P2601 from ARP American Research Products
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RNF114 fusion protein - Ag5649 from Proteintech Group
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RNF114 fusion protein - Ag5915 from Proteintech Group
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RNF114, 1-228aa Human, His tag, E.coli - GWB-ATG0CB from Genway Biotech
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Recombinant Human RNF114, His-tagged - RNF114-31567TH from Creative Biomart
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Recombinant Human RNF114, His-tagged - RNF114-5105H from Creative Biomart
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Recombinant Human RNF114, GST-tagged - RNF114-2334H from Creative Biomart
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Recombinant Human ring finger protein 114, His-tagged - RNF114-504H from Creative Biomart
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Recombinant Human RING finger protein 114(RNF114) - CSB-YP019821HU CSB-EP019821HU CSB-BP019821HU CSB-MP019821HU from Cusabio
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RNF114, 1-228aa, Human, His tag, E.coli (Denatured) - ATGP2601 from ATGen
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RNF114 - TP309752 from Acris Antibodies
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Human RNF114 protein - orb260063 from Biorbyt
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ZNF313 Recombinant Protein Antigen - NBP1-87204PEP from Novus Biologicals
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RNF114 Peptide, Human - M34GP13372H from Creative Peptides
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Recombinant Human ZNF313 Protein - NBP2-51614 from Novus Biologicals
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