RUVBL1

Gene Symbol	RUVBL1
Entrez Gene	8607
Alt Symbol	ECP54, INO80H, NMP238, PONTIN, Pontin52, RVB1, TIH1, TIP49, TIP49A
Species	Human
Gene Type	protein-coding
Description	RuvB-like AAA ATPase 1
Other Description	49 kDa TATA box-binding protein-interacting protein|49 kDa TBP-interacting protein|54 kDa erythrocyte cytosolic protein|ECP-54|INO80 complex subunit H|NMP 238|RuvB (E coli homolog)-like 1|TAP54-alpha|TATA binding protein interacting protein 49 kDa|TIP60-associated protein 54-alpha|nuclear matrix protein 238|pontin 52|ruvB-like 1
Swissprots	Q53HK5 Q9BSX9 Q1KMR0 Q9Y265 P82276 Q53Y27 B2R5S0 Q53HL7
Accessions	AAM45570 EAW79323 Q9Y265 AB012122 BAA28169 AB451224 BAG70038 AB451347 BAG70161 AF070735 AAC77819 AF099084 AAD04427 AJ010058 CAA08986 AK092163 BAG52489 AK222563 BAD96283 AK222575 BAD96295 AK312290 BAG35217 AW069473 BC002993 AAH02993 BC004503 BC012886 AAH12886 BT007057 AAP35706 DA530328 DQ469310 ABF13334 DQ891448 ABM82374 DQ894627 ABM85553 Y18418 CAB46271 XM_005247841 XP_005247898 XM_011513248 XP_011511550 XM_011513249 XP_011511551 XM_011513250 XP_011511552 XR_924202 NM_003707 NP_003698
Function	May be able to bind plasminogen at cell surface and enhance plasminogen activation.
Subcellular Location	Nucleus matrix. Nucleus, nucleoplasm. Cytoplasm. Membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Mainly localized in the nucleus, associated with nuclear matrix or in the nuclear cytosol, although it is also present in the cytoplasm and associated with the cell membranes. In prophase and prometaphase it is located at the centrosome and the branching microtubule spindles. After mitotic nuclear membrane disintigration it accumulates at the centrosome and sites of tubulin polymerization. As cells pass through metaphase and into telophase it is located close to the centrosome at the early phase of tubulin polymerization. In anaphase it accumulates at the zone of tubule interdigitation. In telophase it is found at polar tubule overlap, and it reappears at the site of chromosomal decondensation in the daughter cells.
Tissue Specificity	Ubiquitously expressed with high expression in heart, skeletal muscle and testis.
Top Pathways	Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TIP49 / RUVBL1 ELISA Kit (Sandwich ELISA) - LS-F12521 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.312-20 ng/ml

RuvB-like 1, RUVBL1, Human, ELISA Kit - E3290h from ARP American Research Products Category ELISA Kit Prices $660.00 Sizes 96 t Range 0.312-20 ng/mL

RuvB-like 1 (E. coli) , ELISA Kit - MBS9338198 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rat TIP49 / RUVBL1 ELISA Kit (Custom ELISA) - LS-F19862 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.312-20 ng/ml

Mouse TIP49 / RUVBL1 ELISA Kit (Custom ELISA) - LS-F19863 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.312-20 ng/ml

Human RuvB-like 1 ELISA Kit - abx251613 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Human RuvB-like 1 ELISA Kit - EKE54439 from Biomatik Category ELISA Kit Prices $759.00, $3,225.75, $6,072.00 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.12 ng/mL Range 0.312-20 ng/mL

RUVBL1 - EKH4530 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

RUVBL1 ELISA Kit (Human) (OKEH01702) - OKEH01702 from Aviva Systems Biology Category ELISA Kit Prices $450.00 Sizes 96 wells Sensitivity < 0.12 ng/mL Range 0.312 - 20 ng/mL

Human RUVBL1 ELISA Kit - E034021 from Biobool Category ELISA Kit Sensitivity <0.188ng/ml

Human RuvB-like 1 ELISA Kit - EK4586 from Signalway Antibody Category ELISA Kit Prices $659.00 Sizes 1x96t Sensitivity less than 0.082ng/mL Range 0.156-10 ng/ml

anti-RuVBL1 / TIP49A antibody [1D6] - ARG57073 from Arigo Biolaboratories Category ELISA Kit

RuvB-like 1, ELISA Kit - MBS2886461 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.312-20 ng/mL

RuvB-like 1, ELISA Kit - MBS9428412 from MyBioSource Category ELISA Kit Prices $605.00 Sizes 96 tests Sensitivity Less than 0.12ng/mL Range 0.312-20 ng/mL

Human TIP49 / RUVBL1 ELISA Kit (Sandwich ELISA) - LS-F33714 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.188 Range 0.312-20 ng/ml

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