RUVBL1

Gene Symbol	RUVBL1
Entrez Gene	8607
Alt Symbol	ECP54, INO80H, NMP238, PONTIN, Pontin52, RVB1, TIH1, TIP49, TIP49A
Species	Human
Gene Type	protein-coding
Description	RuvB-like AAA ATPase 1
Other Description	49 kDa TATA box-binding protein-interacting protein|49 kDa TBP-interacting protein|54 kDa erythrocyte cytosolic protein|ECP-54|INO80 complex subunit H|NMP 238|RuvB (E coli homolog)-like 1|TAP54-alpha|TATA binding protein interacting protein 49 kDa|TIP60-associated protein 54-alpha|nuclear matrix protein 238|pontin 52|ruvB-like 1
Swissprots	Q53HK5 Q9BSX9 Q1KMR0 Q9Y265 P82276 Q53Y27 B2R5S0 Q53HL7
Accessions	AAM45570 EAW79323 Q9Y265 AB012122 BAA28169 AB451224 BAG70038 AB451347 BAG70161 AF070735 AAC77819 AF099084 AAD04427 AJ010058 CAA08986 AK092163 BAG52489 AK222563 BAD96283 AK222575 BAD96295 AK312290 BAG35217 AW069473 BC002993 AAH02993 BC004503 BC012886 AAH12886 BT007057 AAP35706 DA530328 DQ469310 ABF13334 DQ891448 ABM82374 DQ894627 ABM85553 Y18418 CAB46271 XM_005247841 XP_005247898 XM_011513248 XP_011511550 XM_011513249 XP_011511551 XM_011513250 XP_011511552 XR_924202 NM_003707 NP_003698
Function	May be able to bind plasminogen at cell surface and enhance plasminogen activation.
Subcellular Location	Nucleus matrix. Nucleus, nucleoplasm. Cytoplasm. Membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Mainly localized in the nucleus, associated with nuclear matrix or in the nuclear cytosol, although it is also present in the cytoplasm and associated with the cell membranes. In prophase and prometaphase it is located at the centrosome and the branching microtubule spindles. After mitotic nuclear membrane disintigration it accumulates at the centrosome and sites of tubulin polymerization. As cells pass through metaphase and into telophase it is located close to the centrosome at the early phase of tubulin polymerization. In anaphase it accumulates at the zone of tubule interdigitation. In telophase it is found at polar tubule overlap, and it reappears at the site of chromosomal decondensation in the daughter cells.
Tissue Specificity	Ubiquitously expressed with high expression in heart, skeletal muscle and testis.
Top Pathways	Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Pontin/RUVBL1 Antibody - 12300 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

Pontin 52 (A-4) - sc-393854 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Pontin 52 (A-11) - sc-393905 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Pontin 52 (H-4) - sc-365339 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Pontin 52 (E-18) - sc-49076 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Pontin 52 (D-15) - sc-49075 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Pontin 52 (H-100) - sc-48798 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Pontin 52 (Q-15) - sc-15260 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Pontin 52 (N-15) - sc-15259 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Pontin 52 (2943C1a) - sc-81360 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

Anti-TIP49A antibody - ab37754 from Abcam Prices $376.00 Sizes 50 µg Host Chicken Clonality Polyclonal

Anti-TIP49A antibody [2943C1a] - ab51500 from Abcam Prices $400.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2943C1a

Anti-TIP49A antibody [EPR4143] - ab108927 from Abcam Prices $379.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR4143

Anti-TIP49A antibody [EPR6028] - ab133513 from Abcam Prices $385.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR6028

Anti-TIP49 / RUVBL1 Antibody (clone 507CT2.2.2, FITC) - LS-C232240 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 507CT2.2.2

Anti-TIP49 / RUVBL1 Antibody (clone 507CT2.2.2, APC) - LS-C232241 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 507CT2.2.2

Anti-TIP49 / RUVBL1 Antibody (clone 507CT2.2.2, PE) - LS-C232242 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 507CT2.2.2

Anti-TIP49 / RUVBL1 Antibody (AP) - LS-C245685 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TIP49 / RUVBL1 Antibody (APC) - LS-C245686 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TIP49 / RUVBL1 Antibody (Biotin) - LS-C245687 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TIP49 / RUVBL1 Antibody (FITC) - LS-C245688 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TIP49 / RUVBL1 Antibody (PE) - LS-C245690 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TIP49 / RUVBL1 Antibody - LS-C158908 from LifeSpan Bioscience Prices $295.00 Sizes 100 µl Host Mouse Clonality Monoclonal

Anti-TIP49 / RUVBL1 Antibody (Azide-free, HRP) - LS-C247835 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TIP49 / RUVBL1 Antibody (clone 507CT2.2.2, Azide-free, HRP) - LS-C249338 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 507CT2.2.2

Search more