POLE3

Gene Symbol	POLE3
Entrez Gene	54107
Alt Symbol	CHARAC17, CHRAC17, YBL1, p17
Species	Human
Gene Type	protein-coding
Description	polymerase (DNA directed), epsilon 3, accessory subunit
Other Description	CHRAC-17|DNA polymerase II subunit 3|DNA polymerase epsilon p17 subunit|DNA polymerase epsilon subunit 3|DNA polymerase epsilon subunit p17|arsenic transactivated protein|arsenic-transactivated protein|asTP|chromatin accessibility complex 17 kDa protein|histone fold protein CHRAC17|huCHRAC17|polymerase (DNA directed), epsilon 3 (p17 subunit)
Swissprots	Q9NR32 Q8NCE5 Q9NRF9 Q8N758 Q5W0U1
Accessions	AAF90133 AAY57326 CAF86695 CAF86796 EAW87381 EAW87382 Q9NRF9 AF070640 AF226077 AAF72417 AK074629 BAC11099 AK074762 BAC11190 AK074782 BAC11206 AK092840 AK096050 AY720898 AAU15052 BC003166 AAH03166 BC004170 AAH04170 DA477404 DA521953 DA908447 JF432738 ADZ15955 NM_001278255 NP_001265184 NM_017443 NP_059139 NR_027261
Function	Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Top Pathways	DNA replication, Base excision repair, Nucleotide excision repair, HTLV-I infection, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DNA Polymerase epsilon peptide - ab135296 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human DNA Polymerase epsilon full length protein - ab156724 from Abcam Category Protein Source E. coli Species Human

CHRAC17 / POLE3 Antibody Blocking Peptide - LS-E8856 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CHRAC17 / POLE3 Antibody Blocking Peptide - LS-E11640 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CHRAC17 / POLE3 Antibody Blocking Peptide - LS-E11641 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CHRAC17 / POLE3 Antibody Blocking Peptide - LS-E21238 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DNA Polymerase epsilon subunit 3 Recombinant Protein - H00054107-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human DNA Polymerase epsilon subunit 3 Protein - NBP2-23341 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

POLE3-Antibody-N-term-Blocking-Peptide - BP7316a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human POLE3 protein - orb191211 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

POLE3 protein (His tag) - 80R-2846 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

POLE3 (1-147, His-tag) - AR50965PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

POLE3 (1-147, His-tag) - AR50965PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

POLE3 - H00054107-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

POLE3 - H00054107-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

POLE3, 1-147aa, Human, His tag, E.coli - 01-P2141 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

POLE3 Recombinant Protein - XW-RP3196 from ProSci Category Protein Prices $475.00 Sizes 100 µg Source E. coli Species Human

POLE3 fusion protein - ag7871 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

POLE3 fusion protein - Ag7396 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human POLE3, His-tagged - POLE3-397H from Creative Biomart Category Protein Source E.Coli.

Recombinant Human POLE3, His-tagged - POLE3-28362TH from Creative Biomart Category Protein Source E. coli

Recombinant Human POLE3, His-tagged - POLE3-7630H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human DNA polymerase epsilon subunit 3(POLE3) - CSB-YP878866HU CSB-EP878866HU CSB-BP878866HU CSB-MP878866HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

POLE3, 1-147aa, Human, His tag, E.coli - ATGP2141 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

POLE3 - TP300874 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

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