POLE3

Gene Symbol POLE3
Entrez Gene 54107
Alt Symbol CHARAC17, CHRAC17, YBL1, p17
Species Human
Gene Type protein-coding
Description polymerase (DNA directed), epsilon 3, accessory subunit
Other Description CHRAC-17|DNA polymerase II subunit 3|DNA polymerase epsilon p17 subunit|DNA polymerase epsilon subunit 3|DNA polymerase epsilon subunit p17|arsenic transactivated protein|arsenic-transactivated protein|asTP|chromatin accessibility complex 17 kDa protein|histone fold protein CHRAC17|huCHRAC17|polymerase (DNA directed), epsilon 3 (p17 subunit)
Swissprots Q9NR32 Q8NCE5 Q9NRF9 Q8N758 Q5W0U1
Accessions AAF90133 AAY57326 CAF86695 CAF86796 EAW87381 EAW87382 Q9NRF9 AF070640 AF226077 AAF72417 AK074629 BAC11099 AK074762 BAC11190 AK074782 BAC11206 AK092840 AK096050 AY720898 AAU15052 BC003166 AAH03166 BC004170 AAH04170 DA477404 DA521953 DA908447 JF432738 ADZ15955 NM_001278255 NP_001265184 NM_017443 NP_059139 NR_027261
Function Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Top Pathways DNA replication, Base excision repair, Nucleotide excision repair, HTLV-I infection, Purine metabolism

CHRAC17 CRISPR/Cas9 KO Plasmid (h) - sc-407797 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHRAC17 HDR Plasmid (h) - sc-407797-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHRAC17 Double Nickase Plasmid (h) - sc-407797-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHRAC17 Double Nickase Plasmid (h2) - sc-407797-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHRAC17 CRISPR Activation Plasmid (h) - sc-407797-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHRAC17 CRISPR Activation Plasmid (h2) - sc-407797-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHRAC17 Lentiviral Activation Particles (h) - sc-407797-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHRAC17 Lentiviral Activation Particles (h2) - sc-407797-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHRAC17 siRNA (h) - sc-38615 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CHRAC17 shRNA Plasmid (h) - sc-38615-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CHRAC17 shRNA (h) Lentiviral Particles - sc-38615-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU045281 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17096 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17096 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

POLE3 siRNA (Human) - CRJ0022 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DNA Polymerase epsilon subunit 3 RNAi - H00054107-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human POLE3 (NM_017443.4) - SHH379188 from Creative biogene

Category siRNA
Species Reactivities Human

POLE3 shRNA Plasmid (Human) - CHJ0022 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

POLE3 miRNA 3'UTR clone - MiUTR3H-09097 from Creative biogene

Species Reactivities Human
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