POLE3

Gene Symbol POLE3
Entrez Gene 54107
Alt Symbol CHARAC17, CHRAC17, YBL1, p17
Species Human
Gene Type protein-coding
Description polymerase (DNA directed), epsilon 3, accessory subunit
Other Description CHRAC-17|DNA polymerase II subunit 3|DNA polymerase epsilon p17 subunit|DNA polymerase epsilon subunit 3|DNA polymerase epsilon subunit p17|arsenic transactivated protein|arsenic-transactivated protein|asTP|chromatin accessibility complex 17 kDa protein|histone fold protein CHRAC17|huCHRAC17|polymerase (DNA directed), epsilon 3 (p17 subunit)
Swissprots Q9NR32 Q8NCE5 Q9NRF9 Q8N758 Q5W0U1
Accessions AAF90133 AAY57326 CAF86695 CAF86796 EAW87381 EAW87382 Q9NRF9 AF070640 AF226077 AAF72417 AK074629 BAC11099 AK074762 BAC11190 AK074782 BAC11206 AK092840 AK096050 AY720898 AAU15052 BC003166 AAH03166 BC004170 AAH04170 DA477404 DA521953 DA908447 JF432738 ADZ15955 NM_001278255 NP_001265184 NM_017443 NP_059139 NR_027261
Function Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Top Pathways DNA replication, Base excision repair, Nucleotide excision repair, HTLV-I infection, Purine metabolism

CHRAC17 (D-1) - sc-393397 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CHRAC17 (D-1): sc-393397. Western blot analysis of CHRAC17 expression in non-transfected 293T: sc-117752 (A), mouse CHRAC17 transfected 293T: sc-125134 (B), HeLa (C) and Hep G2 (D) whole cell lysates.

CHRAC17 (E-11) - sc-376242 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CHRAC17 (E-11): sc-376242. Western blot analysis of CHRAC17 expression in non-transfected: sc-117752 (A) and mouse CHRAC17 transfected: sc-125134 (B) 293T whole cell lysates.

CHRAC17 (F-19) - sc-13465 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CHRAC17 (N-15) - sc-13463 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-DNA Polymerase epsilon antibody - ab88521 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-DNA Polymerase epsilon antibody (ab88521) at 1 µg/ml + Human liver tissue lysate at 50 µg

Anti-POLE3 / DNA Polymerase Epsilon Antibody (aa5-34) - LS-C100903 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
POLE3 Antibody western blot of K562 cell line lysates (35 ug/lane). The POLE3 antibody detected the POLE3 protein (arrow).

Anti-POLE3 / DNA Polymerase Epsilon Antibody (aa97-147) - LS-C286497 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse PolE3/p17 by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-PolE3/p17 used at a dilution of 1:100.

Anti-CHRAC17 / POLE3 Antibody (aa97-147) - LS-C92026 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-POLE3 / DNA Polymerase Epsilon Antibody (clone 3C5.1, Biotin) - LS-C140794 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 3C5.1

Anti-POLE3 / DNA Polymerase Epsilon Antibody (clone 3C5.1, DY650) - LS-C140795 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 3C5.1

Anti-CHRAC17 / POLE3 Antibody (clone 3C5.1, HRP) - LS-C140797 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 3C5.1

Anti-POLE3 / DNA Polymerase Epsilon Antibody (clone 3C5.1, DY550) - LS-C140798 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 3C5.1

Anti-POLE3 / DNA Polymerase Epsilon Antibody (clone 3C5.1, DY488) - LS-C140796 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 3C5.1

Anti-POLE3 / DNA Polymerase Epsilon Antibody (N-Terminus) - LS-C30573 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Daudi Cell Lysate

Anti-POLE3 / DNA Polymerase Epsilon Antibody (N-Terminus) - LS-C102743 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
POLE3 antibody LS-C102743 Western blot of Fetal Lung lysate.

Anti-POLE3 / DNA Polymerase Epsilon Antibody (clone 3C5.1) - LS-C2650 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 3C5.1
SDS-polyacrylamide gel analysis of HeLa DNA pol purified by Mono S FPLC. The Mono S fraction of HeLa DNA pol (0.1 mg) was electrophoresed on a 7% SDS-polyacrylamide gel and stained with silver.

Anti-POLE3 / DNA Polymerase Epsilon Antibody - LS-C335676 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of U2OS cell using POLE3 antibody.

Anti-POLE3 / DNA Polymerase Epsilon Antibody (aa97-147) - LS-C288056 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse PolE3/p17 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti-PolE3/p17 used at a dilution of 1:5000 (0.2 ug/ml). Detection: DAB.

Anti-POLE3 / DNA Polymerase Epsilon Antibody (C-Terminus) - LS-C146393 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
POLE3 antibody LS-C146393 Western blot of Mouse Liver lysate. Antibody concentration 1 ug/ml.

DNA Polymerase epsilon catalytic subunit A Antibody (3C5.1) - NB100-115 from Novus Biologicals

Prices $129.00, $299.00
Sizes 25 µl, 50 µl
Host Mouse
Clonality Monoclonal
Clone 3C5.1
Western Blot: DNA Polymerase epsilon catalytic subunit A Antibody (3C5.1) [NB100-115] - SDS-polyacrylamide gel analysis. Antibody was purified by Mono S FPLC. The Mono S fraction (0.1 mg) was electrophoresed on a 7% SDS-polyacrylamide gel and stained with silver.

DNA Polymerase epsilon subunit 3 Antibody - NB100-60438 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DNA Polymerase epsilon subunit 3 Antibody [NB100-60438] - Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells.  NB100-60438 used for WB at 0.4 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate.

DNA Polymerase epsilon subunit 3 Antibody - H00054107-B02 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: DNA Polymerase epsilon Antibody [H00054107-B02] - POLE3 MaxPab polyclonal antibody (B02), Lot # 07320WULz. Western Blot analysis of POLE3 expression in human liver.

DNA Polymerase epsilon subunit 3 Antibody - H00054107-B02P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: DNA Polymerase epsilon subunit 3 Antibody [H00054107-B02P] - Analysis of POLE3 expression in human liver.

DNA Polymerase epsilon subunit 3 Antibody - H00054107-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: DNA Polymerase epsilon Antibody [H00054107-B01] - analysis of POLE3 expression in transfected 293T cell line by POLE3 MaxPab polyclonal antibody (B01). Lane 1: POLE3 transfected lysate (16.28 KDa). Lane 2: Non-transfected lysate.

DNA Polymerase epsilon subunit 3 Antibody - H00054107-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Search more