FCGR3A

Gene Symbol FCGR3A
Entrez Gene 2214
Alt Symbol CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20
Species Human
Gene Type protein-coding
Description Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Other Description CD16a antigen|Fc fragment of IgG, low affinity III, receptor for (CD16)|Fc gamma receptor III-A|Fc-gamma RIII-alpha|Fc-gamma RIIIa|Fc-gamma receptor III-2 (CD 16)|Fc-gamma receptor IIIb (CD16)|FcgammaRIIIA|fc-gamma RIII|igG Fc receptor III-2|immunoglobulin G Fc receptor III|low affinity immunoglobulin gamma Fc region receptor III-A|neutrophil-specific antigen NA
Swissprots Q53FL6 A2N6W9 P08637 Q6PIJ0 Q65ZM6 Q53FJ0 Q5EBR4
Accessions AAD48438 ACS66838 ACS66839 ACS66840 ACS66841 ACS66842 ACS66843 ACS66844 ACS66845 BAA86888 CAA86295 CBL93996 P08637 AK223268 BAD96988 AK223295 BAD97015 AK302126 BAG63503 BC017865 AAH17865 BC033678 AAH33678 BC036723 AAH36723 BI768140 DA674960 DA933259 DA944383 DA957430 HQ447137 ADQ31624 M24853 AAA53506 S62490 S76824 AAB33925 X52645 CAA36870 XM_011509293 XP_011507595 NM_000569 NP_000560 NM_001127592 NP_001121064 NM_001127593 NP_001121065 NM_001127595 NP_001121067 NM_001127596 NP_001121068
Function Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. {ECO:0000269|PubMed:21768335, ECO:0000269|PubMed:22023369}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Secreted. Note=Exists also as a soluble receptor.
Tissue Specificity Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
Top Pathways Natural killer cell mediated cytotoxicity, Systemic lupus erythematosus, Fc gamma R-mediated phagocytosis, Leishmaniasis, Phagosome

CD16 (FcgammaIII) (CB-16) Mouse mAb - 3567 from Cell Signaling Technology

Host Mouse
Clonality Monoclonal
Clone CB-16
Flow cytometric analysis of whole blood using CD16 (CB-16) Mouse mAb.

CD16 (H-80) - sc-20627 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD16 (H-80): sc-20627. Western blot analysis of CD16 expression in K-562 (A), U-937 (B) and JEG-3 (C) whole cell lysates.

CD16 (DJ130c) - sc-20052 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD16 (DJ130c) FITC: sc-20052 FITC. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2855.

CD16 (3G8) - sc-19620 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD16 (3G8) PE: sc-19620 PE. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

CD16 (Y-15) - sc-19357 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CD16 (YFC 120.5) - sc-58962 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
CD16 (YFC 120.5): sc-58962. Western blot analysis of CD16 expression in human PBL (A,B) whole cell lysates under reducing (B) and non-reducing (A) conditions.

CD16 (GRM1) - sc-19594 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD16 (GRM1): sc-19594. Western blot analysis of CD16 expression in human PBL whole cell lysate.

CD16 (MEM-154) - sc-51525 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CD16 (MEM-154): sc-51525. Indirect FCM analysis of human peripheral blood leukocytes stained with CD16 (MEM-154), followed by PE-conjugated goat anti-mouse IgG<sub>1</sub>: sc-3764. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-3877.

CD16 (LNK16) - sc-51524 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CD16 (LNK16): sc-51524. Indirect FCM analysis of human peripheral blood leukocytes stained with CD16 (LNK16), followed by PE-conjugated goat anti-mouse IgG<sub>1</sub>: sc-3764. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-3877.

CD16 (B-E16) - sc-65294 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CD16 (B-E16): sc-65294. Indirect FCM analysis of human peripheral blood leukocytes stained with CD16 (B-E16), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG<sub>2a</sub>: sc-3878.

CD16 (2Q1240) - sc-70548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD16 (2Q1240): sc-70548. Western blot analysis of CD16 expression in non-transfected: sc-117752 (A) and human CD16 transfected: sc-114183 (B) 293T whole cell lysates.

CD16 (ASH 1975) - sc-52376 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CD16 (ASH 1975): sc-52376. Indirect FCM analysis of human peripheral blood leukocytes stained with CD16 (ASH 1975), followed by PE-conjugated goat anti-mouse IgG<sub>2a</sub>: sc-3765. Black line histogram represents the isotype control, normal mouse IgG<sub>2a</sub>: sc-3878.

CD16-B (Z64) - sc-73799 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-CD16 antibody - ab198169 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue labeling CD16 with ab198169 at a 1/40 dilution.

Anti-CD16 antibody - ab90545 from Abcam

Prices $376.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Anti-CD16 antibody (ab90545) at 1/500 dilution + immunogen (238aa recombinant fragment with a tag of 26kDa) at 0.2 µg

Anti-CD16 antibody - ab94773 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD16 antibody (ab94773) at 1 µg/mlLane 1 : Bone Marrow (Human) Tissue Lysate - adult normal tissueLane 2 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lane 3 : Thymus (Human) Tissue Lysate - adult normal tissue (ab30146)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CD16 antibody - ab125477 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CD16 antibody (ab125477) at 1 µg/ml + Human placenta lysate at 10 µg

Anti-CD16 antibody [0.N.82] - ab33515 from Abcam

Prices $376.00
Sizes 250 µl
Host Mouse
Clonality Monoclonal
Clone 0.N.82
Formalin-fixed, paraffin-embedded human tonsil stained with ab33515 using peroxidase-conjugate and AEC chromogen. Note membrane staining of granulocytes.Staining requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 minutes, followed by cooling at RT for 20 minutes.

Anti-CD16 antibody [2H7], prediluted - ab74512 from Abcam

Prices $378.00
Sizes 7 ml
Host Mouse
Clonality Monoclonal
Clone 2H7
Formalin-fixed, paraffin-embedded human tonsil stained with ab74512 using peroxidase-conjugate and AEC chromogen. Note membrane staining of granulocytes.

Anti-CD16 antibody [3G8] - ab117271 from Abcam

Prices $376.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 3G8
Flow cytometry data on peripheral blood (healthy individual) stained with the ab117271 at 20µl/106 cells. The reagent allows to identify the NK cell subset CD16+ with low SSC, and DC cells CD16+. Red histogram represents Granulocyte cells, blue histogram represents Dendritic and Monocyte cells and yellow histogram represents lymphocytic cells and NK cells.

Anti-CD16 antibody [3G8] (Alexa Fluor® 488) - ab187585 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 3G8

Anti-CD16 antibody [3G8] (Allophycocyanin) - ab140477 from Abcam

Prices $185.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 3G8

Anti-CD16 antibody [3G8] (PerCP) - ab130761 from Abcam

Prices $185.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 3G8

Anti-CD16 antibody [3G8] (Phycoerythrin) - ab117117 from Abcam

Prices $372.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 3G8

Anti-CD16 antibody [3G8], prediluted (Allophycocyanin/Cy7 ®) - ab197141 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 3G8
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