FCGR3A

Gene Symbol	FCGR3A
Entrez Gene	2214
Alt Symbol	CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20
Species	Human
Gene Type	protein-coding
Description	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Other Description	CD16a antigen|Fc fragment of IgG, low affinity III, receptor for (CD16)|Fc gamma receptor III-A|Fc-gamma RIII-alpha|Fc-gamma RIIIa|Fc-gamma receptor III-2 (CD 16)|Fc-gamma receptor IIIb (CD16)|FcgammaRIIIA|fc-gamma RIII|igG Fc receptor III-2|immunoglobulin G Fc receptor III|low affinity immunoglobulin gamma Fc region receptor III-A|neutrophil-specific antigen NA
Swissprots	Q53FL6 A2N6W9 P08637 Q6PIJ0 Q65ZM6 Q53FJ0 Q5EBR4
Accessions	AAD48438 ACS66838 ACS66839 ACS66840 ACS66841 ACS66842 ACS66843 ACS66844 ACS66845 BAA86888 CAA86295 CBL93996 P08637 AK223268 BAD96988 AK223295 BAD97015 AK302126 BAG63503 BC017865 AAH17865 BC033678 AAH33678 BC036723 AAH36723 BI768140 DA674960 DA933259 DA944383 DA957430 HQ447137 ADQ31624 M24853 AAA53506 S62490 S76824 AAB33925 X52645 CAA36870 XM_011509293 XP_011507595 NM_000569 NP_000560 NM_001127592 NP_001121064 NM_001127593 NP_001121065 NM_001127595 NP_001121067 NM_001127596 NP_001121068
Function	Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. {ECO:0000269|PubMed:21768335, ECO:0000269|PubMed:22023369}.
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Secreted. Note=Exists also as a soluble receptor.
Tissue Specificity	Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
Top Pathways	Natural killer cell mediated cytotoxicity, Systemic lupus erythematosus, Fc gamma R-mediated phagocytosis, Leishmaniasis, Phagosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FCGR3A-Over-expression-Lysate - LY12627a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

FCGR3A 293T Cell Transient Overexpression Lysate(Denatured) - H00002214-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

FCGR3A overexpression lysate - LY426815 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

FCGR3A overexpression lysate - LY426817 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

FCGR3A 293 Cell Lysate - 400265 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Fc gamma RIIIA/CD16a Overexpression Lysate (Denatured) - H00002214-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Fc gamma RIIIA/CD16a Overexpression Lysate (Native) - NBL1-10658 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CD16 (h): 293T Lysate - sc-114183 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

FCGR3A Over-expression Lysate Product - GWB-58D764 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Rhesus CD16 / FCGR3 HEK293 Cell Lysate (WB positive control) - 90013-C27HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Rhesus

Rhesus CD16 / FCGR3 HEK293 Cell Lysate (WB positive control) - 90013-C08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Rhesus

Human CD16a / FCGR3A HEK293 Cell Lysate (WB positive control) - 10389-H27HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human CD16a / FCGR3A HEK293 Cell Lysate (WB positive control) - 10389-H27H1L-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human CD16a / FCGR3A HEK293 Cell Lysate (WB positive control) - 10389-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human CD16a / FCGR3A HEK293 Cell Lysate (WB positive control) - 10389-H08H1L-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human CD16a / FCGR3A CHO Cell Lysate (WB positive control) - 10389-H08CL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human CD16a / FCGR3A CHO Cell Lysate (WB positive control) - 10389-H08C1L-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human CD16a CHO Transfected Lysate (positive control) (denatured) - orb175347 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Human CD16a Human Cells Transfected Lysate (positive control) (denatured) - orb172862 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Fc gamma RIIIA/CD16a Overexpression Lysate (Native) - NBP2-11370 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Human CD16a Human Cells Transfected Lysate (positive control) (denatured) - orb173744 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human CD16a Human Cells Transfected Lysate (positive control) (denatured) - orb173745 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human CD16a CHO Transfected Lysate (positive control) (denatured) - orb175348 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human CD16a Human Cells Transfected Lysate (positive control) (denatured) - orb173746 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human FCGR3A Knockdown Stable Cell Line - CSC-DC005641 from Creative biogene Category Cell Line Species Human

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