FCGR3A

Gene Symbol	FCGR3A
Entrez Gene	2214
Alt Symbol	CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20
Species	Human
Gene Type	protein-coding
Description	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Other Description	CD16a antigen|Fc fragment of IgG, low affinity III, receptor for (CD16)|Fc gamma receptor III-A|Fc-gamma RIII-alpha|Fc-gamma RIIIa|Fc-gamma receptor III-2 (CD 16)|Fc-gamma receptor IIIb (CD16)|FcgammaRIIIA|fc-gamma RIII|igG Fc receptor III-2|immunoglobulin G Fc receptor III|low affinity immunoglobulin gamma Fc region receptor III-A|neutrophil-specific antigen NA
Swissprots	Q53FL6 A2N6W9 P08637 Q6PIJ0 Q65ZM6 Q53FJ0 Q5EBR4
Accessions	AAD48438 ACS66838 ACS66839 ACS66840 ACS66841 ACS66842 ACS66843 ACS66844 ACS66845 BAA86888 CAA86295 CBL93996 P08637 AK223268 BAD96988 AK223295 BAD97015 AK302126 BAG63503 BC017865 AAH17865 BC033678 AAH33678 BC036723 AAH36723 BI768140 DA674960 DA933259 DA944383 DA957430 HQ447137 ADQ31624 M24853 AAA53506 S62490 S76824 AAB33925 X52645 CAA36870 XM_011509293 XP_011507595 NM_000569 NP_000560 NM_001127592 NP_001121064 NM_001127593 NP_001121065 NM_001127595 NP_001121067 NM_001127596 NP_001121068
Function	Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. {ECO:0000269|PubMed:21768335, ECO:0000269|PubMed:22023369}.
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Secreted. Note=Exists also as a soluble receptor.
Tissue Specificity	Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
Top Pathways	Natural killer cell mediated cytotoxicity, Systemic lupus erythematosus, Fc gamma R-mediated phagocytosis, Leishmaniasis, Phagosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human CD16 protein fragment - ab167758 from Abcam Category Protein Prices $465.00 Sizes 100 µg Source HEK 293 cells Species Human

CD16 peptide - ab202990 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human CD16 (biotinylated ) protein fragment - ab197648 from Abcam Category Protein Source HEK 293 cells Species Human

Human CD16 protein fragment - ab151819 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source HEK 293 cells Species Human

Human CD16 protein fragment - ab130057 from Abcam Category Protein Prices $297.00 Sizes 100 µg Source E. coli Species Human

Fc gamma RIIIA/CD16a Recombinant Protein - H00002214-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Fc gamma RIIIA/CD16a Protein - NBP1-98908 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E.coli Species Human

Fc gamma RIIIA/CD16a Recombinant Protein - H00002214-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

FCGR3A-Antibody-C-term-Blocking-peptide - BP13534b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Fc gamma RIIIA/CD16a, CF - 4325-FC-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Gly17-Gln208, with a C-terminal 6-His tag

Cynomolgus CD16 His tag protein - orb84274 from Biorbyt Category Protein Prices $434.00, $646.00 Sizes 50 μg, 100 μg Source Human

Human CD16a His AVI tag protein - orb84282 from Biorbyt Category Protein Prices $400.00, $646.00 Sizes 20 μg, 50 μg Source Human Species Human

Human CD16a His AVI tag protein - orb84266 from Biorbyt Category Protein Prices $434.00, $646.00 Sizes 50 μg, 100 μg Source Human Species Human

Human FCGR3A protein - orb168335 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human CD16a His tag (176 Phe/Val) protein - orb84265 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human CD16a protein (His Tag) - orb138362 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source CHO Cells Species Human

Cynomolgus CD16 His AVI tag protein - orb84273 from Biorbyt Category Protein Prices $434.00, $646.00 Sizes 50 μg, 100 μg Source Human

Human CD16a His tag protein - orb82956 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human CD16a protein - orb49382 from Biorbyt Category Protein Prices $272.00, $366.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human CD16a His AVI tag (176 Phe/Val) protein - orb84281 from Biorbyt Category Protein Prices $357.00, $612.00 Sizes 20 μg, 50 μg Source Human Species Human

Human CD16a His AVI tag (176 Phe/Val) protein - orb84267 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Cynomolgus CD16 His AVI tag protein - orb84289 from Biorbyt Category Protein Prices $400.00, $646.00 Sizes 20 μg, 50 μg Source Human

Human CD16a protein (His Tag) - orb138361 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source CHO Cells Species Human

FCGR3A protein (His tag) - 80R-2366 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

Human FcgR3A Protein - abx066541 from Abbexa Category Protein Source E.coli Species Human

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