FCGR3A

Gene Symbol FCGR3A
Entrez Gene 2214
Alt Symbol CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20
Species Human
Gene Type protein-coding
Description Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Other Description CD16a antigen|Fc fragment of IgG, low affinity III, receptor for (CD16)|Fc gamma receptor III-A|Fc-gamma RIII-alpha|Fc-gamma RIIIa|Fc-gamma receptor III-2 (CD 16)|Fc-gamma receptor IIIb (CD16)|FcgammaRIIIA|fc-gamma RIII|igG Fc receptor III-2|immunoglobulin G Fc receptor III|low affinity immunoglobulin gamma Fc region receptor III-A|neutrophil-specific antigen NA
Swissprots Q53FL6 A2N6W9 P08637 Q6PIJ0 Q65ZM6 Q53FJ0 Q5EBR4
Accessions AAD48438 ACS66838 ACS66839 ACS66840 ACS66841 ACS66842 ACS66843 ACS66844 ACS66845 BAA86888 CAA86295 CBL93996 P08637 AK223268 BAD96988 AK223295 BAD97015 AK302126 BAG63503 BC017865 AAH17865 BC033678 AAH33678 BC036723 AAH36723 BI768140 DA674960 DA933259 DA944383 DA957430 HQ447137 ADQ31624 M24853 AAA53506 S62490 S76824 AAB33925 X52645 CAA36870 XM_011509293 XP_011507595 NM_000569 NP_000560 NM_001127592 NP_001121064 NM_001127593 NP_001121065 NM_001127595 NP_001121067 NM_001127596 NP_001121068
Function Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. {ECO:0000269|PubMed:21768335, ECO:0000269|PubMed:22023369}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Secreted. Note=Exists also as a soluble receptor.
Tissue Specificity Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
Top Pathways Natural killer cell mediated cytotoxicity, Systemic lupus erythematosus, Fc gamma R-mediated phagocytosis, Leishmaniasis, Phagosome

CD16 CRISPR/Cas9 KO Plasmid (h) - sc-400544 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16 HDR Plasmid (h) - sc-400544-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16 Double Nickase Plasmid (h) - sc-400544-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16 Double Nickase Plasmid (h2) - sc-400544-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16 CRISPR Activation Plasmid (h) - sc-400544-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16 CRISPR Activation Plasmid (h2) - sc-400544-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16 Lentiviral Activation Particles (h) - sc-400544-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16 Lentiviral Activation Particles (h2) - sc-400544-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16 siRNA (h) - sc-42758 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD16 shRNA Plasmid (h) - sc-42758-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD16 shRNA (h) Lentiviral Particles - sc-42758-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Fc gamma RIIIA/CD16a RNAi - H00002214-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU110711 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8592 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8592 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FCGR3A siRNA (Human) - CRH1548 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FCGR3A - MBS8233365 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Fcgr3 (NM_000569.6) - SHH293734 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FCGR3A(NM_000569.6) - SHH054569 from Creative biogene

Category siRNA
Species Reactivities Human

CD16 CRISPR/Cas9 KO Plasmid (h2) - sc-400544-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD16 HDR Plasmid (h2) - sc-400544-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human FCGR3A siRNA - orb262050 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FCGR3A shRNA Plasmid (Human) - CHH1548 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FCGR3A miRNA 3'UTR clone - MiUTR1H-03595 from Creative biogene

Species Reactivities Human

FCGR3A miRNA 3'UTR clone - MiUTR3H-01154 from Creative biogene

Species Reactivities Human
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