PRAME

Gene Symbol	PRAME
Entrez Gene	23532
Alt Symbol	CT130, MAPE, OIP-4, OIP4
Species	Human
Gene Type	protein-coding
Description	preferentially expressed antigen in melanoma
Other Description	Opa-interacting protein OIP4|cancer/testis antigen 130|melanoma antigen preferentially expressed in tumors|opa-interacting protein 4|preferentially expressed antigen of melanoma
Swissprots	O43481 B2R6Y7 Q8IXN8 P78395
Accessions	EAW59518 EAW59519 EAW59520 EAW59521 EAW59522 EAW59523 P78395 AF025440 AAC39560 AI613210 AK129783 AK302188 BAH13644 AK304593 BAH14222 AK312769 BAG35634 AK316395 BAH14766 BC014074 AAH14074 BC022008 AAH22008 BC039731 AAH39731 BM015464 BQ432004 BU151249 CF121110 CR456549 CAG30435 CU013149 CAK54580 CU013437 CAK54879 DB024053 DC395455 DQ893473 ABM84399 DQ896327 ABM87326 JQ511981 AFX65483 JQ511982 AFX65484 JQ511983 AFX65485 JQ511984 AFX65486 JQ511985 AFX65487 U65011 AAC51160 XM_011530034 XP_011528336 XM_011530035 XP_011528337 XM_011546897 XP_011545199 XM_011546898 XP_011545200 NM_001291715 NP_001278644 NM_001291716 NP_001278645 NM_001291717 NP_001278646 NM_001291719 NP_001278648 NM_006115 NP_006106 NM_206953 NP_996836 NM_206954 NP_996837 NM_206955 NP_996838 NM_206956 NP_996839
Function	Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. {ECO:0000269|PubMed:16179254}.
Subcellular Location	Nucleus {ECO:0000305|PubMed:16620968}. Cell membrane {ECO:0000269|PubMed:16620968}.
Tissue Specificity	Expressed in testis. Detected in samples of kidney, brain and skin. {ECO:0000269|PubMed:9047241}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PRAME full length protein - ab132315 from Abcam Category Protein Source Wheat germ Species Human

Human PRAME protein fragment - ab181886 from Abcam Category Protein Source E. coli Species Human

PRAME Antibody Blocking Peptide - LS-E8415 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRAME Antibody Blocking Peptide - LS-E20271 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRAME Antibody Blocking Peptide - LS-E20272 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PRAME Protein - H00023532-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MAPE-Antibody-C-term-Blocking-Peptide - BP6720b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human PRAME protein - orb245962 from Biorbyt Category Protein Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human PRAME protein - orb244456 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

PRAME Blocking Peptide - 33R-1390 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PRAME Blocking Peptide - 33R-5955 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human PRAME Protein - abx068652 from Abbexa Category Protein Source E.coli Species Human

Human PRAME Protein - abx068653 from Abbexa Category Protein Source E.coli Species Human

PRAME / MAPE - AR60005PU-N from Acris Antibodies Category Protein Prices $205.00 Sizes 20 µg Source E. coli Species Human

PRAME / MAPE - H00023532-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PRAME / MAPE - H00023532-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Preferentially Expressed Antigen In Melanoma - 20-9244 from ARP American Research Products Category Protein Prices $545.00 Sizes 50 µg Source E.coli Species Human

Preferentially Expressed Antigen In Melanoma - 20-9245 from ARP American Research Products Category Protein Prices $545.00 Sizes 50 µg Source E.coli Species Human

PRAME fusion protein - ag1906 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Preferentially Expressed Antigen In Melanoma (PRAME) - RPH323Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Preferentially Expressed Antigen In Melanoma (PRAME) - RPH323Hu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Preferentially Expressed Antigen In Melanoma (PRAME) - RPH323Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Preferentially Expressed Antigen In Melanoma (PRAME) - RPH323Hu02 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant human Melanoma antigen preferentially expressed in tumors - CSB-EP018603HU CSB-BP018603HU CSB-MP018603HU from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Melanoma antigen preferentially expressed in tumors(PRAME) - CSB-YP018603HU CSB-BP018603HU CSB-MP018603HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

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