PRAME

Gene Symbol PRAME
Entrez Gene 23532
Alt Symbol CT130, MAPE, OIP-4, OIP4
Species Human
Gene Type protein-coding
Description preferentially expressed antigen in melanoma
Other Description Opa-interacting protein OIP4|cancer/testis antigen 130|melanoma antigen preferentially expressed in tumors|opa-interacting protein 4|preferentially expressed antigen of melanoma
Swissprots O43481 B2R6Y7 Q8IXN8 P78395
Accessions EAW59518 EAW59519 EAW59520 EAW59521 EAW59522 EAW59523 P78395 AF025440 AAC39560 AI613210 AK129783 AK302188 BAH13644 AK304593 BAH14222 AK312769 BAG35634 AK316395 BAH14766 BC014074 AAH14074 BC022008 AAH22008 BC039731 AAH39731 BM015464 BQ432004 BU151249 CF121110 CR456549 CAG30435 CU013149 CAK54580 CU013437 CAK54879 DB024053 DC395455 DQ893473 ABM84399 DQ896327 ABM87326 JQ511981 AFX65483 JQ511982 AFX65484 JQ511983 AFX65485 JQ511984 AFX65486 JQ511985 AFX65487 U65011 AAC51160 XM_011530034 XP_011528336 XM_011530035 XP_011528337 XM_011546897 XP_011545199 XM_011546898 XP_011545200 NM_001291715 NP_001278644 NM_001291716 NP_001278645 NM_001291717 NP_001278646 NM_001291719 NP_001278648 NM_006115 NP_006106 NM_206953 NP_996836 NM_206954 NP_996837 NM_206955 NP_996838 NM_206956 NP_996839
Function Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. {ECO:0000269|PubMed:16179254}.
Subcellular Location Nucleus {ECO:0000305|PubMed:16620968}. Cell membrane {ECO:0000269|PubMed:16620968}.
Tissue Specificity Expressed in testis. Detected in samples of kidney, brain and skin. {ECO:0000269|PubMed:9047241}.

PRAME CRISPR/Cas9 KO Plasmid (h) - sc-404682 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRAME HDR Plasmid (h) - sc-404682-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRAME Double Nickase Plasmid (h) - sc-404682-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRAME Double Nickase Plasmid (h2) - sc-404682-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRAME CRISPR Activation Plasmid (h) - sc-404682-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRAME CRISPR Activation Plasmid (h2) - sc-404682-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRAME Lentiviral Activation Particles (h) - sc-404682-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRAME Lentiviral Activation Particles (h2) - sc-404682-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRAME siRNA (h) - sc-37322 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRAME shRNA Plasmid (h) - sc-37322-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRAME shRNA (h) Lentiviral Particles - sc-37322-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU098961 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU092851 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17336 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17336 from Sigma-Aldrich

Category ZFN Kit
Prices $4,120.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03049 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03049

PRAME siRNA (Human) - CRH8337 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PRAME(NM_006115.3) - SHR136640 from Creative biogene

Category siRNA
Species Reactivities Human

Human PRAME siRNA - orb268839 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PRAME shRNA Plasmid (Human) - CHH8337 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PRAME miRNA 3'UTR clone - MiUTR1H-08211 from Creative biogene

Species Reactivities Human

PRAME miRNA 3'UTR clone - MiUTR3H-08142 from Creative biogene

Species Reactivities Human
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