PRAME

Gene Symbol PRAME
Entrez Gene 23532
Alt Symbol CT130, MAPE, OIP-4, OIP4
Species Human
Gene Type protein-coding
Description preferentially expressed antigen in melanoma
Other Description Opa-interacting protein OIP4|cancer/testis antigen 130|melanoma antigen preferentially expressed in tumors|opa-interacting protein 4|preferentially expressed antigen of melanoma
Swissprots O43481 B2R6Y7 Q8IXN8 P78395
Accessions EAW59518 EAW59519 EAW59520 EAW59521 EAW59522 EAW59523 P78395 AF025440 AAC39560 AI613210 AK129783 AK302188 BAH13644 AK304593 BAH14222 AK312769 BAG35634 AK316395 BAH14766 BC014074 AAH14074 BC022008 AAH22008 BC039731 AAH39731 BM015464 BQ432004 BU151249 CF121110 CR456549 CAG30435 CU013149 CAK54580 CU013437 CAK54879 DB024053 DC395455 DQ893473 ABM84399 DQ896327 ABM87326 JQ511981 AFX65483 JQ511982 AFX65484 JQ511983 AFX65485 JQ511984 AFX65486 JQ511985 AFX65487 U65011 AAC51160 XM_011530034 XP_011528336 XM_011530035 XP_011528337 XM_011546897 XP_011545199 XM_011546898 XP_011545200 NM_001291715 NP_001278644 NM_001291716 NP_001278645 NM_001291717 NP_001278646 NM_001291719 NP_001278648 NM_006115 NP_006106 NM_206953 NP_996836 NM_206954 NP_996837 NM_206955 NP_996838 NM_206956 NP_996839
Function Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. {ECO:0000269|PubMed:16179254}.
Subcellular Location Nucleus {ECO:0000305|PubMed:16620968}. Cell membrane {ECO:0000269|PubMed:16620968}.
Tissue Specificity Expressed in testis. Detected in samples of kidney, brain and skin. {ECO:0000269|PubMed:9047241}.

PRAME (D-12) - sc-166480 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PRAME (D-12): sc-166480. Western blot analysis of PRAME expression in non-transfected: sc-117752 (A) and human PRAME transfected: sc-115478 (B) 293T whole cell lysates.

PRAME (E-19) - sc-34512 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PRAME (E-19): sc-34512. Western blot analysis of PRAME expression in NTERA-2 cl.D1 (A), K-562 (B), HeLa (C), HEK293 (D) and MDA-MB-435S (E) whole cell lysates.

PRAME (H-10) - sc-137188 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PRAME (H-10): sc-137188. Western blot analysis of PRAME expression in non-transfected: sc-117752 (A) and human PRAME transfected: sc-115478 (B) 293T whole cell lysates.

PRAME (H-80) - sc-67041 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PRAME (H-80): sc-67041. Western blot analysis of PRAME expression in non-transfected: sc-117752 (A) and human PRAME transfected: sc-115478 (B) 293T whole cell lysates.

PRAME (C-16) - sc-19081 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PRAME antibody - ab89097 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-PRAME antibody (ab89097) at 1 µg/ml + HeLa cell lysate at 50 µg

Anti-PRAME antibody - ab90053 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PRAME antibody (ab90053) at 1 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PRAME antibody - ab90052 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PRAME antibody (ab90052) at 1 µg/ml + Human fetal brain lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PRAME antibody - C-terminal - ab135600 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded Human testis tissue labelling PRAME with ab135600 at 1/50 dilution followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-PRAME Antibody (aa148-163) - LS-C148037 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-PRAME Antibody (aa416-502, Biotin) - LS-C299879 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PRAME Antibody (aa416-502, Biotin) - LS-C301253 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PRAME Antibody (aa416-502, FITC) - LS-C302036 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PRAME Antibody - LS-C47362 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of PRAME in MCF7 cell lysate. Lane 1 shows pre-immune sera. Lane 2 shows antibody tested at 1:5000 dilution.

Anti-PRAME Antibody (aa416-502, FITC) - LS-C302209 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PRAME Antibody (aa1-100) - LS-C83868 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of PRAME in MCF7 cell lysates.

Anti-PRAME Antibody (N-Terminus) - LS-C111765 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PRAME antibody LS-C111765 Western blot of Fetal Brain lysate.

Anti-PRAME Antibody (aa71-120) - LS-C111766 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PRAME antibody LS-C111766 Western blot of HepG2 cell lysate.

Anti-PRAME Antibody (aa416-502) - LS-C296014 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PRAME.

Anti-PRAME Antibody (aa1-300) - LS-C334732 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of U2OS cell using PRAME antibody. Blue: DAPI for nuclear staining.

Anti-PRAME Antibody (aa416-502) - LS-C296018 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PRAME.

Anti-PRAME Antibody IHC-plus™ - LS-B10827 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-PRAME antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10827 concentration 7.5 ug/ml.

Anti-PRAME Antibody (aa476-502) - LS-C164013 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MAPE Antibody (RB18763) IHC of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

PRAME Antibody - NBP2-23670 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal

PRAME Antibody - NBP1-85418 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PRAME Antibody [NBP1-85418] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
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