DOC2A

Gene Symbol	DOC2A
Entrez Gene	8448
Alt Symbol	Doc2
Species	Human
Gene Type	protein-coding
Description	double C2-like domains, alpha
Other Description	doc2-alpha|double C2-like domain-containing protein alpha
Swissprots	Q7Z5G0 Q8IVX0 Q6P4G4 B4DEJ2 Q14183 H3BNH6
Accessions	EAW79942 EAW79943 EAW79944 EAW79945 EAW79946 EAW79947 EAW79948 EAW79949 EAW79950 EAW79951 EAW79952 Q14183 AK090829 AK293651 BAG57103 AK309158 BC041769 AAH41769 BC055284 AAH55284 BC063436 AAH63436 BI757951 BX460259 D31897 BAA06695 DC399462 XM_005255635 XP_005255692 XM_006721099 XP_006721162 XM_011545972 XP_011544274 XM_011545973 XP_011544275 XM_011545974 XP_011544276 XM_011545975 XP_011544277 NM_001282062 NP_001268991 NM_001282063 NP_001268992 NM_001282068 NP_001268997 NM_003586 NP_003577 NR_104089 NR_104090
Function	Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. {ECO:0000269|PubMed:18354201, ECO:0000269|PubMed:9736751, ECO:0000269|PubMed:9804756}.
Subcellular Location	Lysosome {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Cell junction, synapse, synaptosome. Note=Colocalizes to synaptic vesicles.
Tissue Specificity	Predominantly expressed in brain. Also expressed in testis. {ECO:0000269|PubMed:7826360, ECO:0000269|PubMed:8554557}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DOC2A full length protein - ab160033 from Abcam Category Protein Source Wheat germ Species Human

DOC2A Antibody Blocking Peptide - LS-E1983 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DOC2A Antibody Blocking Peptide - LS-E23600 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DOC2A Antibody Blocking Peptide - LS-E27768 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Doc2-alpha Protein - H00008448-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DOC2A-Antibody-Center-Blocking-peptide - BP12839c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Goat anti DOC2A antibody Immunizing peptide - orb65215 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

DOC2A Peptide - AC21-2580-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

DOC2A - H00008448-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DOC2A - H00008448-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DOC2A Peptide - 42-893P from ProSci Category Peptide

DOC2A fusion protein - ag4876 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

DOC2A fusion protein - Ag5415 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Double C2-like domain-containing protein alpha(DOC2A) - CSB-YP617905HU CSB-EP617905HU CSB-BP617905HU CSB-MP617905HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DOC2A, Peptide - MBS427547 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

DOC2A Peptide, Human - M34GP04470H from Creative Peptides Category Peptide Source Synthetic. Species Human

Doc2-alpha Recombinant Protein Antigen - NBP2-55903PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Double C2-like domain-containing protein alpha (DOC2A), Recombinant Protein - MBS1296442 from MyBioSource Category Protein Prices $1,170.00, $1,170.00, $1,390.00, $1,390.00, $1,880.00, $1,880.00, $2,345.00, $2,345.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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