USP22

Gene Symbol	USP22
Entrez Gene	23326
Alt Symbol	USP3L
Species	Human
Gene Type	protein-coding
Description	ubiquitin specific peptidase 22
Other Description	deubiquitinating enzyme 22|ubiquitin carboxyl-terminal hydrolase 22|ubiquitin specific protease 22|ubiquitin thioesterase 22|ubiquitin thiolesterase 22|ubiquitin-specific processing protease 22|ubiquitin-specific-processing protease 22
Swissprots	A0JNS3 Q9UPT9 Q8TBS8 Q6MZY4 Q96IW5 Q2NLE2
Accessions	Q9UPT9 AB028986 BAA83015 AK025331 AK130677 AL049258 AL110213 BC007196 AAH07196 BC013364 BC025317 AAH25317 BC050994 BC084550 BC110499 AAI10500 BC126898 AAI26899 BX640815 CAE45893 DQ581604 XM_005256575 XP_005256632 NM_015276 NP_056091
Function	Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression. {ECO:0000269|PubMed:18206972, ECO:0000269|PubMed:18206973, ECO:0000269|PubMed:18469533}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver. {ECO:0000269|PubMed:16378762}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human USP22 protein fragment - ab127325 from Abcam Category Protein Source E. coli Species Human

USP22 Antibody Blocking Peptide - LS-E21340 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP22 Antibody Blocking Peptide - LS-E6897 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP22 Antibody Blocking Peptide - LS-E6898 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP22 Peptide - P0947 from Novus Biologicals Category Peptide Species Human

USP22 Peptide - P0948 from Novus Biologicals Category Peptide Species Human

USP22-Antibody-C-term-Blocking-Peptide - BP2148b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP22-Antibody-N-term-Blocking-Peptide - BP2148a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP22 Blocking Peptide - 33R-8029 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

USP22 Blocking Peptide - 33R-7372 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 22(USP22) - CSB-YP891982HU CSB-EP891982HU CSB-BP891982HU CSB-MP891982HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

USP22 Recombinant Protein Antigen - NBP1-82941PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

USP22 Peptide, Human - M34GP17166H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Human His6-USP22 Protein, CF - E-608 from R&D Systems Category Protein Prices $269.00 Sizes 50 µg Source Spodoptera frugiperda , Sf 21 (baculovirus)-derived Contains an N-terminal 6-His tag Species Human

Recombinant Human His6-USP22 Protein, CF - E-608 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Species Human

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