USP22

Gene Symbol USP22
Entrez Gene 23326
Alt Symbol USP3L
Species Human
Gene Type protein-coding
Description ubiquitin specific peptidase 22
Other Description deubiquitinating enzyme 22|ubiquitin carboxyl-terminal hydrolase 22|ubiquitin specific protease 22|ubiquitin thioesterase 22|ubiquitin thiolesterase 22|ubiquitin-specific processing protease 22|ubiquitin-specific-processing protease 22
Swissprots A0JNS3 Q9UPT9 Q8TBS8 Q6MZY4 Q96IW5 Q2NLE2
Accessions Q9UPT9 AB028986 BAA83015 AK025331 AK130677 AL049258 AL110213 BC007196 AAH07196 BC013364 BC025317 AAH25317 BC050994 BC084550 BC110499 AAI10500 BC126898 AAI26899 BX640815 CAE45893 DQ581604 XM_005256575 XP_005256632 NM_015276 NP_056091
Function Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression. {ECO:0000269|PubMed:18206972, ECO:0000269|PubMed:18206973, ECO:0000269|PubMed:18469533}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver. {ECO:0000269|PubMed:16378762}.

USP22 (C-16) - sc-69082 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

USP22 (C-3) - sc-390585 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
USP22 (C-3): sc-390585. Western blot analysis of USP22 expression in HeLa (A) and Jurkat (B) whole cell lysates.

USP22 (D-13) - sc-69083 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
USP22 (D-13): sc-69083. Western blot analysis of USP22 expression in HeLa (A) and Jurkat (C) whole cell lysates and HeLa nuclear extract (B).

USP22 (H-47) - sc-292319 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-USP22 antibody - ab4812 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-USP22 antibody (ab4812) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 2 : HeLa (Human epithelial carcinoma cell line) Nuclear Lysate Lane 3 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate Lane 4 : Jurkat (Human T cell lymphoblast-like cell line) Nuclear Lysate (ab14844)Lane 5 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 6 : HepG2 (Human hepatocellular liver carcinoma cell line) Nuclear Lysate (ab14660)Lane 7 : A431 (Human epithelial carcinoma cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilutionPerformed under reducing conditions.

Anti-USP22 antibody - ab82986 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-USP22 antibody (ab82986) at 1 µg/ml + Fetal heart lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-USP22 antibody [EPR4352(2)] - ab109435 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4352(2)
All lanes : Anti-USP22 antibody [EPR4352(2)] (ab109435) at 1/1000 dilutionLane 1 : HeLa lysateLane 2 : Human placenta lysateLane 3 : HT-1376 lysateLysates/proteins at 10 µg per lane.

Anti-USP22 Antibody (aa100-205, Biotin) - LS-C143523 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (aa100-205, DY488) - LS-C143525 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (aa100-205, HRP) - LS-C143526 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (aa100-205, DY650) - LS-C143524 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (aa100-205, DY550) - LS-C143527 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (aa295-513) - LS-C178925 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (C-Terminus, AP) - LS-C221091 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (C-Terminus, APC) - LS-C221092 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (C-Terminus, FITC) - LS-C221093 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (N-Terminus, AP) - LS-C221094 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (N-Terminus, APC) - LS-C221095 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (C-Terminus, PE) - LS-C221096 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (N-Terminus, FITC) - LS-C221097 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (N-Terminus, PE) - LS-C221098 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (N-Terminus) - LS-C329065 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (N-Terminus) - LS-C329067 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP22 Antibody (aa72-121) - LS-C102769 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
USP22 antibody LS-C102769 Western blot of Fetal Heart lysate.

Anti-USP22 Antibody - LS-C332051 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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