Gene Symbol | FICD |
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Entrez Gene | 11153 |
Alt Symbol | HIP13, HYPE, UNQ3041 |
Species | Human |
Gene Type | protein-coding |
Description | FIC domain containing |
Other Description | AMPylator FICD|FIC domain-containing protein|HIP-13|Huntingtin interacting protein E|adenosine monophosphate-protein transferase FICD|fic S-phase protein cell division homolog|huntingtin interacting protein 13|huntingtin interactor protein E|huntingtin yeast partner E|huntingtin-interacting protein 13|huntingtin-interacting protein E |
Swissprots | Q9BVA6 O75406 |
Accessions | EAW97813 EAW97814 EAW97815 Q9BVA6 AF049611 AAC26847 AK000014 AK026074 AY358992 AAQ89351 BC001342 AAH01342 BC064629 DQ891787 ABM82713 EU176625 ABW03426 XM_011537793 XP_011536095 NM_007076 NP_009007 |
Function | Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified. {ECO:0000269|PubMed:19362538, ECO:0000269|PubMed:22266942}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:19362538}. |
HYPE cDNA (ANA10288) - ANA10288 from Aviva Systems Biology
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HYPE cDNA (ANA10446) - ANA10446 from Aviva Systems Biology
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HYPE cDNA (ANA10447) - ANA10447 from Aviva Systems Biology
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FICD - MBS1273317 from MyBioSource
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Human FICD cDNA clone(NM_007076.2) - CDFH006898 from Creative Biomart
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Human FICD ORF Clone(NM_007076.2) - CDCR294353 from Creative Biomart
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Human FICD ORF Clone(NM_007076.2) - CDCR294354 from Creative Biomart
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Human FICD ORF Clone(NM_007076.2) - CDCR294355 from Creative Biomart
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Human FICD ORF Clone(NM_007076.2) - CDCL163550 from Creative Biomart
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Human FICD ORF Clone(NM_007076.2) - CDCL163551 from Creative Biomart
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Human FICD ORF clone - CDCL108367 from Creative Biomart
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Human FICD ORF clone - CDCL108368 from Creative Biomart
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Human FICD ORF clone - CDCL108369 from Creative Biomart
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Human FICD ORF clone - CDCL108370 from Creative Biomart
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Human FICD ORF Clone(NM_007076.2) - CDCR294353 from Creative biogene
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Human FICD ORF Clone (BC001342) - CDCS413061 from Creative biogene
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Human FICD cDNA Clone(NM_007076.2) - CDFH006898 from Creative biogene
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