Gene Symbol | FICD |
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Entrez Gene | 11153 |
Alt Symbol | HIP13, HYPE, UNQ3041 |
Species | Human |
Gene Type | protein-coding |
Description | FIC domain containing |
Other Description | AMPylator FICD|FIC domain-containing protein|HIP-13|Huntingtin interacting protein E|adenosine monophosphate-protein transferase FICD|fic S-phase protein cell division homolog|huntingtin interacting protein 13|huntingtin interactor protein E|huntingtin yeast partner E|huntingtin-interacting protein 13|huntingtin-interacting protein E |
Swissprots | Q9BVA6 O75406 |
Accessions | EAW97813 EAW97814 EAW97815 Q9BVA6 AF049611 AAC26847 AK000014 AK026074 AY358992 AAQ89351 BC001342 AAH01342 BC064629 DQ891787 ABM82713 EU176625 ABW03426 XM_011537793 XP_011536095 NM_007076 NP_009007 |
Function | Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified. {ECO:0000269|PubMed:19362538, ECO:0000269|PubMed:22266942}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:19362538}. |
Human HYPE full length protein - ab161327 from Abcam
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HYPE / FICD Antibody Blocking Peptide - LS-E17031 from LifeSpan Bioscience
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HYPE / FICD Antibody Blocking Peptide - LS-E17032 from LifeSpan Bioscience
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Recombinant Human HYPE Protein - H00011153-P01 from Novus Biologicals
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HYPE Protein Lysate (APL10288) - APL10288 from Aviva Systems Biology
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HYPE Protein Lysate (APL10446) - APL10446 from Aviva Systems Biology
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HYPE Protein Lysate (APL10447) - APL10447 from Aviva Systems Biology
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FICD Blocking Peptide - 33R-3215 from Fitzgerald
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FICD Blocking Peptide - 33R-2836 from Fitzgerald
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HYPE Peptide - AC21-2477-P from Abcore
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HIP13 / FICD - H00011153-P01-02 from Acris Antibodies
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FICD Peptide - 42-842P from ProSci
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FICD fusion protein - Ag2597 from Proteintech Group
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Recombinant Human FICD, GST-tagged - FICD-12894H from Creative Biomart
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FIC domain containing (FICD) - TP301725 from Acris Antibodies
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HYPE/FICD, Peptide - MBS427457 from MyBioSource
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HYPE Protein - NBP1-89697PEP from Novus Biologicals
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HYPE Protein Lysate - orb333366 from Biorbyt
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HYPE Protein Lysate - orb333245 from Biorbyt
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FICD Peptide, Human - M34GP05743H from Creative Peptides
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HYPE Recombinant Protein Antigen - NBP2-58855PEP from Novus Biologicals
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