FICD

Gene Symbol FICD
Entrez Gene 11153
Alt Symbol HIP13, HYPE, UNQ3041
Species Human
Gene Type protein-coding
Description FIC domain containing
Other Description AMPylator FICD|FIC domain-containing protein|HIP-13|Huntingtin interacting protein E|adenosine monophosphate-protein transferase FICD|fic S-phase protein cell division homolog|huntingtin interacting protein 13|huntingtin interactor protein E|huntingtin yeast partner E|huntingtin-interacting protein 13|huntingtin-interacting protein E
Swissprots Q9BVA6 O75406
Accessions EAW97813 EAW97814 EAW97815 Q9BVA6 AF049611 AAC26847 AK000014 AK026074 AY358992 AAQ89351 BC001342 AAH01342 BC064629 DQ891787 ABM82713 EU176625 ABW03426 XM_011537793 XP_011536095 NM_007076 NP_009007
Function Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified. {ECO:0000269|PubMed:19362538, ECO:0000269|PubMed:22266942}.
Subcellular Location Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:19362538}.

Human HYPE full length protein - ab161327 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161327 on a 12.5% SDS-PAGE stained with Coomassie Blue.

HYPE / FICD Antibody Blocking Peptide - LS-E17031 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

HYPE / FICD Antibody Blocking Peptide - LS-E17032 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human HYPE Protein - H00011153-P01 from Novus Biologicals

Category Protein
Prices $305.00, $445.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

HYPE Protein Lysate (APL10288) - APL10288 from Aviva Systems Biology

Category Protein
Prices $219.00
Sizes 200 µg

HYPE Protein Lysate (APL10446) - APL10446 from Aviva Systems Biology

Category Protein
Prices $219.00
Sizes 200 µg

HYPE Protein Lysate (APL10447) - APL10447 from Aviva Systems Biology

Category Protein
Prices $219.00
Sizes 200 µg

FICD Blocking Peptide - 33R-3215 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

FICD Blocking Peptide - 33R-2836 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

HYPE Peptide - AC21-2477-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

HIP13 / FICD - H00011153-P01-02 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Source in vitro transl.
Species Human

FICD Peptide - 42-842P from ProSci

Category Peptide

FICD fusion protein - Ag2597 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human FICD, GST-tagged - FICD-12894H from Creative Biomart

Category Protein
Source E.coli
Species Human

FIC domain containing (FICD) - TP301725 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
FIC domain containing (FICD)

HYPE/FICD, Peptide - MBS427457 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse, Rat, Dog, Pig, Bovine

HYPE Protein - NBP1-89697PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

HYPE Protein Lysate - orb333366 from Biorbyt

Category Protein
Prices $400.00
Sizes 200 μg
Species Human

HYPE Protein Lysate - orb333245 from Biorbyt

Category Protein
Prices $400.00
Sizes 200 μg
Species Human

FICD Peptide, Human - M34GP05743H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

HYPE Recombinant Protein Antigen - NBP2-58855PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human
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