Gene Symbol | FICD |
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Entrez Gene | 11153 |
Alt Symbol | HIP13, HYPE, UNQ3041 |
Species | Human |
Gene Type | protein-coding |
Description | FIC domain containing |
Other Description | AMPylator FICD|FIC domain-containing protein|HIP-13|Huntingtin interacting protein E|adenosine monophosphate-protein transferase FICD|fic S-phase protein cell division homolog|huntingtin interacting protein 13|huntingtin interactor protein E|huntingtin yeast partner E|huntingtin-interacting protein 13|huntingtin-interacting protein E |
Swissprots | Q9BVA6 O75406 |
Accessions | EAW97813 EAW97814 EAW97815 Q9BVA6 AF049611 AAC26847 AK000014 AK026074 AY358992 AAQ89351 BC001342 AAH01342 BC064629 DQ891787 ABM82713 EU176625 ABW03426 XM_011537793 XP_011536095 NM_007076 NP_009007 |
Function | Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified. {ECO:0000269|PubMed:19362538, ECO:0000269|PubMed:22266942}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:19362538}. |
HYPE (T-12) - sc-132716 from Santa Cruz Biotechnology
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HYPE (G-24) - sc-101979 from Santa Cruz Biotechnology
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Anti-HYPE antibody - ab176776 from Abcam
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Anti-HYPE antibody - ab67163 from Abcam
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Anti-HYPE antibody [2A12] - ab180484 from Abcam
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Anti-HYPE / FICD Antibody - LS-C307547 from LifeSpan Bioscience
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Anti-HYPE / FICD Antibody - LS-C307548 from LifeSpan Bioscience
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Anti-HYPE / FICD Antibody (aa351-400) - LS-C80940 from LifeSpan Bioscience
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Anti-HYPE / FICD Antibody (aa61-265, clone 3G3) - LS-C338612 from LifeSpan Bioscience
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Anti-HYPE / FICD Antibody (aa61-265, clone 2A12) - LS-C336706 from LifeSpan Bioscience
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Anti-HYPE / FICD Antibody (aa61-265, clone 15E10) - LS-C336735 from LifeSpan Bioscience
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Anti-HYPE / FICD Antibody (aa61-265, clone 2A11) - LS-C340556 from LifeSpan Bioscience
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Anti-HYPE / FICD Antibody (aa61-265, clone 3E3) - LS-C336733 from LifeSpan Bioscience
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Anti-HYPE / FICD Antibody (aa61-265, clone 11E11) - LS-C338609 from LifeSpan Bioscience
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Anti-HYPE / FICD Antibody (C-Terminus) - LS-C80941 from LifeSpan Bioscience
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HYPE Antibody - NBP1-58290 from Novus Biologicals
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HYPE Antibody - NBP1-58294 from Novus Biologicals
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HYPE Antibody - NBP1-89697 from Novus Biologicals
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HYPE Antibody - H00011153-B01P from Novus Biologicals
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HYPE Antibody (3F5) - H00011153-M02 from Novus Biologicals
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HYPE/HIP13 Polyclonal Antibody - bs-11698R from Bioss
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HYPE/HIP13 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11698R-A350 from Bioss
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HYPE/HIP13 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11698R-A488 from Bioss
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HYPE/HIP13 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11698R-A555 from Bioss
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HYPE/HIP13 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11698R-A647 from Bioss
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