FICD

Gene Symbol FICD
Entrez Gene 11153
Alt Symbol HIP13, HYPE, UNQ3041
Species Human
Gene Type protein-coding
Description FIC domain containing
Other Description AMPylator FICD|FIC domain-containing protein|HIP-13|Huntingtin interacting protein E|adenosine monophosphate-protein transferase FICD|fic S-phase protein cell division homolog|huntingtin interacting protein 13|huntingtin interactor protein E|huntingtin yeast partner E|huntingtin-interacting protein 13|huntingtin-interacting protein E
Swissprots Q9BVA6 O75406
Accessions EAW97813 EAW97814 EAW97815 Q9BVA6 AF049611 AAC26847 AK000014 AK026074 AY358992 AAQ89351 BC001342 AAH01342 BC064629 DQ891787 ABM82713 EU176625 ABW03426 XM_011537793 XP_011536095 NM_007076 NP_009007
Function Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified. {ECO:0000269|PubMed:19362538, ECO:0000269|PubMed:22266942}.
Subcellular Location Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:19362538}.

HYPE (T-12) - sc-132716 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HYPE (T-12): sc-132716. Western blot analysis of HYPE expression in Hep G2 whole cell lysate.

HYPE (G-24) - sc-101979 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
HYPE (G-24): sc-101979. Western blot analysis of HYPE expression in Hep G2 whole cell lysate.

Anti-HYPE antibody - ab176776 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human fetal brain tissue labeling HYPE with ab176776 at 1/100 dilution.

Anti-HYPE antibody - ab67163 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-HYPE antibody (ab67163) at 1/500 dilution + human placenta tissue lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

Anti-HYPE antibody [2A12] - ab180484 from Abcam

Prices $357.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A12
All lanes : Anti-HYPE antibody [2A12] (ab180484) at 1/2000 dilutionLane 1 : HEK293T cells were transfected with the pCMV6-ENTRY controlLane 2 : Lysates from HEK293T cells transfected with pCMV6-ENTRY HYPE cDNALysates/proteins at 5 µg per lane.

Anti-HYPE / FICD Antibody - LS-C307547 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-HYPE / FICD Antibody - LS-C307548 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HYPE / FICD Antibody (aa351-400) - LS-C80940 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane A: Marker. Lane B: HepG2 cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%.

Anti-HYPE / FICD Antibody (aa61-265, clone 3G3) - LS-C338612 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3G3
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FICD (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FICD.

Anti-HYPE / FICD Antibody (aa61-265, clone 2A12) - LS-C336706 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A12
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FICD (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FICD.

Anti-HYPE / FICD Antibody (aa61-265, clone 15E10) - LS-C336735 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 15E10
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FICD (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FICD.

Anti-HYPE / FICD Antibody (aa61-265, clone 2A11) - LS-C340556 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A11
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FICD (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FICD.

Anti-HYPE / FICD Antibody (aa61-265, clone 3E3) - LS-C336733 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E3
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FICD (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FICD.

Anti-HYPE / FICD Antibody (aa61-265, clone 11E11) - LS-C338609 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 11E11
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FICD (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FICD.

Anti-HYPE / FICD Antibody (C-Terminus) - LS-C80941 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
FICD / HYPE antibody LS-C80941 was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.

HYPE Antibody - NBP1-58290 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HYPE Antibody [NBP1-58290] - Transfected 293T, Antibody Titration: 0.2-1 ug/ml

HYPE Antibody - NBP1-58294 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: HYPE Antibody [NBP1-58294] - HepG2 cell lysate, concentration 2.5 ug/ml.

HYPE Antibody - NBP1-89697 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HYPE Antibody [NBP1-89697] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted)

HYPE Antibody - H00011153-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: HYPE Antibody [H00011153-B01P] - Analysis of HYPE expression in human placenta.

HYPE Antibody (3F5) - H00011153-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3F5
Western Blot: HYPE Antibody (3F5) [H00011153-M02] - Analysis of FICD expression in transfected 293T cell line by HYPE monoclonal antibody (M02), clone 3F5.Lane 1: FICD transfected lysate (Predicted MW: 51.8 KDa).Lane 2: Non-transfected lysate.

HYPE/HIP13 Polyclonal Antibody - bs-11698R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HYPE/HIP13 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11698R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HYPE/HIP13 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11698R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HYPE/HIP13 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11698R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HYPE/HIP13 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11698R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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