Gene Symbol | SLC22A12 |
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Entrez Gene | 116085 |
Alt Symbol | OAT4L, RST, URAT1 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 22 (organic anion/urate transporter), member 12 |
Other Description | organic anion transporter 4-like protein|renal-specific transporter|solute carrier family 22 (organic anion/cation transporter), member 12|solute carrier family 22 member 12|urate anion exchanger 1|urate transporter 1 |
Swissprots | Q19PF8 Q19PF7 G3XAN7 Q96DT2 Q96S37 Q19PF9 B7WPG1 Q19PG0 Q6UXW3 |
Accessions | AAK68156 ABF74569 ABF74570 ABF74571 ABF74572 ABF74573 CAC51145 EAW74271 EAW74272 EAW74273 EAW74274 EAW74275 EAW74276 Q96S37 AB050269 BAB68364 AB071863 BAB96750 AK055737 BAG51565 AK122599 BAG53617 AK309588 AK315061 AY358183 AAQ88550 BC026291 AAH26291 BC053348 AAH53348 BX104022 DA631511 DQ655911 DQ655912 XM_006718430 XP_006718493 XM_006718431 XP_006718494 NM_001276326 NP_001263255 NM_001276327 NP_001263256 NM_144585 NP_653186 NM_153378 NP_700357 |
Function | Required for efficient urate re-absorption in the kidney. Regulates blood urate levels. Mediates saturable urate uptake by facilitating the exchange of urate against organic anions. {ECO:0000269|PubMed:12024214}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:12024214}; Multi-pass membrane protein {ECO:0000269|PubMed:12024214}. Note=Detected in the luminal membrane of the epithelium of renal proximal tubules. |
Tissue Specificity | Detected in kidney (at protein level). Detected in fetal and adult kidney. Detected in epithelial cells of proximal tubules in renal cortex. {ECO:0000269|PubMed:12024214, ECO:0000269|PubMed:15304510}. |
SLC22A12 (H-64) - sc-368329 from Santa Cruz Biotechnology
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SLC22A12 (S-12) - sc-162201 from Santa Cruz Biotechnology
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Anti-SLC22A12 antibody - ab121826 from Abcam
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Anti-SLC22A12 antibody [EPR12312(2)] - ab181237 from Abcam
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Anti-SLC22A12 antibody - C-terminal - ab198791 from Abcam
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Anti-URAT1 / SLC22A12 Antibody - LS-C179254 from LifeSpan Bioscience
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Anti-URAT1 / SLC22A12 Antibody (C-Terminus) - LS-C18428 from LifeSpan Bioscience
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Anti-URAT1 / SLC22A12 Antibody (C-Terminus) - LS-C18427 from LifeSpan Bioscience
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Anti-URAT1 / SLC22A12 Antibody (aa35-84) - LS-C110859 from LifeSpan Bioscience
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Anti-URAT1 / SLC22A12 Antibody - LS-C335533 from LifeSpan Bioscience
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SLC22A12 Antibody - NBP1-82500 from Novus Biologicals
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SLC22A12 Antibody - NBP1-69538 from Novus Biologicals
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SLC22A12 Antibody (2B5) - H00116085-M02 from Novus Biologicals
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Rabbit Anti-URAT1 Polyclonal Antibody - bs-10357R from Bioss
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Rabbit Anti-URAT1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-10357R-A350 from Bioss
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Rabbit Anti-URAT1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-10357R-A488 from Bioss
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Rabbit Anti-URAT1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-10357R-A555 from Bioss
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Rabbit Anti-URAT1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-10357R-A647 from Bioss
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Rabbit Anti-URAT1 Polyclonal Antibody, Cy3 Conjugated - bs-10357R-Cy3 from Bioss
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Rabbit Anti-URAT1 Polyclonal Antibody, Cy5 Conjugated - bs-10357R-Cy5 from Bioss
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Rabbit Anti-URAT1 Polyclonal Antibody, Cy5.5 Conjugated - bs-10357R-Cy5.5 from Bioss
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Rabbit Anti-URAT1 Polyclonal Antibody, Cy7 Conjugated - bs-10357R-Cy7 from Bioss
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Rabbit Anti-URAT1 Polyclonal Antibody, FITC Conjugated - bs-10357R-FITC from Bioss
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Rabbit Anti-URAT1 Polyclonal Antibody, Biotin Conjugated - bs-10357R-Biotin from Bioss
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Rabbit Anti-URAT1 Polyclonal Antibody, HRP Conjugated - bs-10357R-HRP from Bioss
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