Sema7a

Gene Symbol	Sema7a
Entrez Gene	20361
Alt Symbol	2900057C09Rik, CDw108, H-Sema-L, M-Sema-L, Semal
Species	Mouse
Gene Type	protein-coding
Description	sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
Other Description	H-Sema K1|Semaphorin K1|sema K1|sema L|semaphorin-7A|semaphorin-K1|semaphorin-L
Swissprots	O88371 Q9QUR8
Accessions	EDL25928 Q9QUR8 AB017532 BAA75665 AF030699 AAC34262 AF176670 AAD53118 AK019344 AK156123 BAE33594 BC057875 AAH57875 XM_006510888 XP_006510951 XM_006510889 XP_006510952 NM_011352 NP_035482
Function	Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes. {ECO:0000269|PubMed:12879062, ECO:0000269|PubMed:16713976, ECO:0000269|PubMed:17377534}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:17377534}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:17377534}; Extracellular side {ECO:0000269|PubMed:17377534}.
Tissue Specificity	Highly expressed in activated T-cells (at protein level). Highest expression in brain. Lower in heart, thymus, spleen, testis and ovary. The expression increases in late embryonic and postnatal stages. Detected in T-cells. {ECO:0000269|PubMed:16713976, ECO:0000269|PubMed:17377534}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Semaphorin 7A (SEMA7A), Mouse, ELISA Kit - SEB448Mu from ARP American Research Products Category ELISA Kit Prices $704.00 Sizes 96 t Sensitivity 0.108ng/mL Range 0.312-20ng/mL

Semaphorin-7A (SEMA7A), Mouse, ELISA Kit - CSB-EL021000MO from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Semaphorin-7A, Sema7a, Mouse, ELISA Kit - E2274m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Mouse SEMA7A ELISA Kit - MS0090 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse SEMA7A(Semaphorin 7A) ELISA Kit - E-EL-M1043 from Elabscience Category ELISA Kit Sensitivity 0.19 ng/mL Range 0.31—20 ng/mL

Mouse SEMA7A (Semaphorin 7A) CLIA Kit - E-CL-M0606 from Elabscience Category CLIA Kit Sensitivity 37.50 pg/mL Range Average Recovery (%)

semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) , ELISA Kit - MBS935681 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of mouse SEMA7A is typically less than 7.81 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 31.25 pg/ml -2000 pg/ml.

Mouse Semaphorin-7A(SEMA7A) ELISA kit - CSB-EL021000MO from Cusabio Category ELISA Kit Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

Mouse Semaphorin 7A ELISA - E03S0083 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1ng/mL

ELISA Kit for Semaphorin 7A (SEMA7A) - SEB448Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.108ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Semaphorin 3A (SEMA3A) - SEL917Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 6.1pg/mL. Range 15.625-1000pg/mL The standard curve concentrations used for the ELISA's were 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.625pg/mL

Mouse SEMA7A(Semaphorin 7A) ELISA Kit - E-EL-M1043 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.19 ng/mL Range 0.31~20 ng/mL

Mouse IL-2R (Interleukin-2 Receptor) CLIA Kit - E-CL-M0467 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 9.375pg/mL Range 15.625-1000pg/mL

Semaphorin 7A (SEMA7A), Mouse, ELISA Kit - DL-SEMA7A-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 0.312-20 ng/mL

Mouse SEMA7A ELISA Kit - abx572453 from Abbexa Category ELISA Kit Sensitivity 0.108 ng/ml Range 0.313 ng/ml - 20 ng/ml

Mouse Semaphorin-7A (SEMA7A) ELISA Kit - EKC37789 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

SEMA7A - EKM2706 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.313--20ng/ml

Mouse Sema7a ELISA Kit - E067254 from Biobool Category ELISA Kit Sensitivity 0.188ng/mL

Mouse SEMA7A ELISA Kit - EMS0090 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

SEMA7A ELISA Kit (Mouse) (OKCD02882) - OKCD02882 from Aviva Systems Biology Category ELISA Kit Prices $535.00 Sizes 20 ng Sensitivity 0.113 ng/mL Range 0.312-20 ng/mL

Mouse Semaphorin-7A (SEMA7A) ELISA Kit - AE20152MO from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.113 ng/mL Range 0.312-20 ng/mL

Semaphorin 7A (SEMA7A), ELISA Kit - MBS451856 from MyBioSource Category ELISA Kit Prices $410.00, $540.00, $2,380.00, $4,620.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.108ng/mL Range 0.312-20ng/mL

Semaphorin-7A, ELISA Kit - MBS2886258 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse SEMA7A ELISA Kit - orb408619 from Biorbyt Category ELISA Kit Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

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