ING2

Gene Symbol	ING2
Entrez Gene	3622
Alt Symbol	ING1L, p33ING2
Species	Human
Gene Type	protein-coding
Description	inhibitor of growth family, member 2
Other Description	ING1Lp|inhibitor of growth 1-like protein|inhibitor of growth protein 2|p32
Swissprots	B6ZDS1 Q9H160 O95698
Accessions	AAG11396 EAX04689 EAX04690 Q9H160 AB012853 BAA36419 AB196793 BAF30476 AF053537 AAG11395 AJ006851 CAC20567 AK294310 BAH11731 AK314000 BAG36712 BC030128 AAH30128 BM929984 HQ447773 ADQ32258 XM_011531927 XP_011530229 NM_001291959 NP_001278888 NM_001564 NP_001555
Function	Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs). {ECO:0000269|PubMed:11481424, ECO:0000269|PubMed:12859901}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12859901}. Note=Predominantly nuclear. Localized to chromatin and nuclear matrix. Upon reduced PtdIns(5)P levels seems to be released from chromatin and, at least partially, translocated to the cytoplasm.
Tissue Specificity	Widely expressed. Higher expressed in colon- cancer tumor than in normal colon tissues. {ECO:0000269|PubMed:10072587}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ING2 full length protein - ab127136 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human ING2 full length protein - ab116739 from Abcam Category Protein Source Wheat germ Species Human

Human ING2 full length protein - ab171499 from Abcam Category Protein Source E. coli Species Human

Human ING2 peptide - ab22925 from Abcam Category Peptide Species Human

ING2-AntibodyCenter-Blocking-peptide - BP19411c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ING2/ING1L blocking peptide - GTX89918-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Bovine

ING2 protein (His tag) - 80R-3524 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

ING2 Peptide - AC21-0193-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ING2 / ING1L (1-280, His-tag) - AR51212PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

ING2 / ING1L (1-280, His-tag) - AR51212PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

ING2 / ING1L - H00003622-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ING2 / ING1L - H00003622-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ING2,1-280aa, Human, His tag, E.coli - 01-P2391 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

ING2 Peptide - 45-774P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

ING2 fusion protein - Ag2121 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

ING2 fusion protein - ag19291 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human ING2 - ING2-28777TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human inhibitor of growth family, member 2, His-tagged - ING2-308H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Inhibitor of growth protein 2(ING2) - CSB-YP867125HU CSB-EP867125HU CSB-BP867125HU CSB-MP867125HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ING2,1-280aa, Human, His tag, E.coli (Denatured) - ATGP2391 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

ING2 Partial Protein - H00003622-P01 from Novus Biologicals Category Protein Prices $305.00, $445.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ING2 / ING1L - TP302478 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

p33ING2, Recombinant Protein - MBS515229 from MyBioSource Category Protein Prices $260.00, $415.00 Sizes 20 µg, 50 µg Source Sf9 insect cells using baculovirus Species Human

ING2/ING1L, Peptide - MBS426111 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Bovine

ING2 - PAT-82390-1 from Nordic BioSite Category Protein Species Human

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