ING2

Gene Symbol	ING2
Entrez Gene	3622
Alt Symbol	ING1L, p33ING2
Species	Human
Gene Type	protein-coding
Description	inhibitor of growth family, member 2
Other Description	ING1Lp|inhibitor of growth 1-like protein|inhibitor of growth protein 2|p32
Swissprots	B6ZDS1 Q9H160 O95698
Accessions	AAG11396 EAX04689 EAX04690 Q9H160 AB012853 BAA36419 AB196793 BAF30476 AF053537 AAG11395 AJ006851 CAC20567 AK294310 BAH11731 AK314000 BAG36712 BC030128 AAH30128 BM929984 HQ447773 ADQ32258 XM_011531927 XP_011530229 NM_001291959 NP_001278888 NM_001564 NP_001555
Function	Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs). {ECO:0000269|PubMed:11481424, ECO:0000269|PubMed:12859901}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12859901}. Note=Predominantly nuclear. Localized to chromatin and nuclear matrix. Upon reduced PtdIns(5)P levels seems to be released from chromatin and, at least partially, translocated to the cytoplasm.
Tissue Specificity	Widely expressed. Higher expressed in colon- cancer tumor than in normal colon tissues. {ECO:0000269|PubMed:10072587}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ING2 CRISPR/Cas9 KO Plasmid (h) - sc-404193 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ING2 HDR Plasmid (h) - sc-404193-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ING2 Double Nickase Plasmid (h) - sc-404193-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ING2 Double Nickase Plasmid (h2) - sc-404193-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ING2 CRISPR Activation Plasmid (h) - sc-404193-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ING2 CRISPR Activation Plasmid (h2) - sc-404193-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ING2 Lentiviral Activation Particles (h) - sc-404193-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ING2 Lentiviral Activation Particles (h2) - sc-404193-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ING2 siRNA (h) - sc-62503 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ING2 shRNA Plasmid (h) - sc-62503-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ING2 shRNA (h) Lentiviral Particles - sc-62503-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU048041 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10671 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10671 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01147 from Sigma-Aldrich Category miRNA

ING2 siRNA (Human) - CRH2426 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ING2 RNAi - H00003622-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

ING2 - MBS8212364 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ING2 CRISPR/Cas9 KO Plasmid (h2) - sc-404193-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ING2 HDR Plasmid (h2) - sc-404193-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human ING2 (NM_001564.2) - SHH319481 from Creative biogene Category siRNA Species Reactivities Human

Human ING2 siRNA - orb262928 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ING2 shRNA Plasmid (Human) - CHH2426 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ING2 miRNA 3'UTR clone - MiUTR1H-04945 from Creative biogene Species Reactivities Human

Search more