RAB23

Gene Symbol	RAB23
Entrez Gene	51715
Alt Symbol	HSPC137
Species	Human
Gene Type	protein-coding
Description	RAB23, member RAS oncogene family
Other Description	RAB family small GTP binding protein RAB 23|ras-related protein Rab-23
Swissprots	Q9ULC3 B2R9I5 Q8NI06 Q68DJ6 Q9P023
Accessions	EAX04476 EAX04477 EAX04478 EAX04479 Q9ULC3 AB025427 BAB40309 AB034244 BAA87324 AF161486 AAF29101 AF498951 AAM21099 AK311123 AK313796 BAG36532 AU280196 AY585189 AAT79492 BC015021 AAH15021 CR749371 CAH18224 DA021294 DA391757 DA997359 EU832304 ACE87561 EU832388 ACE86873 XM_005249179 XP_005249236 NM_001278666 NP_001265595 NM_001278667 NP_001265596 NM_001278668 NP_001265597 NM_016277 NP_057361 NM_183227 NP_899050 NR_103822
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes. {ECO:0000269|PubMed:22365972, ECO:0000269|PubMed:22452336}.
Subcellular Location	Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell membrane. Cytoplasm. Cytoplasmic vesicle, autophagosome. Endosome membrane {ECO:0000250}. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.
Top Pathways	Hedgehog signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rab 23 (T-17) - sc-169083 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Rab 23 (C-20) - sc-130248 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

Rab 23 (H-157) - sc-292960 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-RAB23 antibody - ab192420 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB23 antibody - ab82165 from Abcam Prices $370.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-RAB23 antibody - ab169491 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-RAB23 antibody - ab98164 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RAB23 antibody - Carboxyterminal end - ab63140 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB23 Antibody - LS-C162365 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Mouse Clonality Monoclonal

Anti-RAB23 Antibody (C-Terminus) IHC-plus™ - LS-B5894 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-RAB23 Antibody (aa35-84) IHC-plus™ - LS-B5872 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-RAB23 Antibody (clone 427CT2.1.1, AP) - LS-C232231 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 427CT2.1.1

Anti-RAB23 Antibody (clone 427CT2.1.1, APC) - LS-C232232 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 427CT2.1.1

Anti-RAB23 Antibody (clone 427CT2.1.1, Biotin) - LS-C232234 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 427CT2.1.1

Anti-RAB23 Antibody (clone 427CT2.1.1, FITC) - LS-C232236 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 427CT2.1.1

Anti-RAB23 Antibody (clone 427CT2.1.1, PE) - LS-C232237 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 427CT2.1.1

Anti-RAB23 Antibody (clone 427CT2.1.1, Azide-free, HRP) - LS-C249337 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 427CT2.1.1

Anti-RAB23 Antibody (clone 427CT2.1.1) - LS-C319199 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 427CT2.1.1

Anti-RAB23 Antibody - LS-C341022 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB23 Antibody (aa219-230) - LS-C87236 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

RAB23 Antibody - NBP1-86367 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RAB23 Antibody - NBP1-58855 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

RAB23 Antibody - H00051715-D01P from Novus Biologicals Prices $399.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

RAB23 Antibody - NBP1-86366 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RAB23 Antibody - NBP1-20965 from Novus Biologicals Prices $299.00 Sizes 100 µg Host Goat Clonality Polyclonal

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