MCL1

Gene Symbol	MCL1
Entrez Gene	4170
Alt Symbol	BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
Species	Human
Gene Type	protein-coding
Description	myeloid cell leukemia 1
Other Description	bcl-2-like protein 3|bcl-2-related protein EAT/mcl1|induced myeloid leukemia cell differentiation protein Mcl-1|myeloid cell leukemia ES|myeloid cell leukemia sequence 1 (BCL2-related)
Swissprots	Q9UHR8 Q07820 Q9HD91 D3DV04 B2R6B2 Q9UNJ1 Q9NRQ4 D3DV03 Q9NRQ3 Q9UHR9 Q9UHR7
Accessions	AAF64255 AAF64256 AAF74821 AAG00896 AAY68220 EAW53538 EAW53539 EAW53540 EAW53541 Q07820 AA453505 AF118124 AAD13299 AF118276 AAF15309 AF118277 AAF15310 AF118278 AAF15311 AF203373 AAG00904 AK294462 BAG57694 AK297217 BAG59700 AK300499 BAG62213 AK304775 BAG65530 AK312508 BAG35409 AK316267 BAH14638 BC017197 AAH17197 BC071897 AAH71897 BC107735 AAI07736 BT006640 AAP35286 CA421486 DQ890628 ABM92245 DQ893795 ABM84721 FJ917536 ACV83304 L08246 NM_001197320 NP_001184249 NM_021960 NP_068779 NM_182763 NP_877495
Function	Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis. {ECO:0000269|PubMed:10766760, ECO:0000269|PubMed:16543145}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Note=Cytoplasmic, associated with mitochondria.
Top Pathways	PI3K-Akt signaling pathway, MicroRNAs in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MCL1 full length protein - ab131682 from Abcam Category Protein Source E. coli Species Human

Human MCL1 peptide - ab39808 from Abcam Category Peptide Species Human

Human MCL1 peptide - ab39809 from Abcam Category Peptide Species Human

MCL1 peptide - ab199979 from Abcam Category Peptide

MCL1 / MCL 1 Antibody Blocking Peptide - LS-E2207 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCL1 / MCL 1 Antibody Blocking Peptide - LS-E2634 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCL1 / MCL 1 Antibody Blocking Peptide - LS-E25729 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCL1 / MCL 1 Antibody Blocking Peptide - LS-E30129 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

MCL1 / MCL 1 Antibody Blocking Peptide - LS-E30130 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

MCL1 / MCL 1 Antibody Blocking Peptide - LS-E30128 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

MCL1-Antibody-BH3-Domain-Specific-Blocking-peptide - BP1312a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MCL1-Antibody-Center-Blocking-peptide - BP13704c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MCL1 blocking peptide - GTX16013-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat, Bovine

Recombinant Human Mcl-1 Western Blot Standard Protein - WBC003 from R&D Systems Category Protein Prices $109.00 Sizes 100 µl Species Human

Human MCL1 protein - orb168792 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

MCL1 peptide - orb217589 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Dog

Mcl1 Blocking Peptide - 33R-10603 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

MCL1 protein (His tag) - 80R-2440 from Fitzgerald Category Protein Prices $395.00 Sizes 50 µg Source E.coli

MCL1 Blocking Peptide - abx062920 from Abbexa Category Peptide Species Human, Dog, Pig

MCL1 Peptide - AC21-0558-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MCL1 (1-327, His-tag) - AR50520PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

MCL1 (1-327, His-tag) - AR50520PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

MCL1 - P5864 from Acris Antibodies Category Protein Prices $580.00 Sizes 50 µg Species Human

MCL1 Control Peptide - AP30547CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

MCL1 Control Peptide - AP30548CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

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