Gene Symbol | GPC6 |
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Entrez Gene | 10082 |
Alt Symbol | OMIMD1 |
Species | Human |
Gene Type | protein-coding |
Description | glypican 6 |
Other Description | glypican proteoglycan 6|glypican-6 |
Swissprots | Q96SG5 A8K279 Q9H1P4 Q9Y625 Q96SG8 |
Accessions | EAX08931 EAX08932 EAX08933 EAX08934 Q9Y625 AF105267 AAD55749 AF111178 AAD31392 AK074741 AK130013 AK290144 BAF82833 AK304338 BAG65183 AY358462 AAQ88827 BC106947 AAI06948 BQ009005 BQ182216 BX640888 XM_011521044 XP_011519346 NM_005708 NP_005699 |
Function | Cell surface proteoglycan that bears heparan sulfate. Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases (By similarity). Enhances migration and invasion of cancer cells through WNT5A signaling. {ECO:0000250, ECO:0000269|PubMed:21871017}. |
Subcellular Location | Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}; Extracellular side {ECO:0000250}. |
Tissue Specificity | Widely expressed. High expression in fetal kidney and lung and lower expressions in fetal liver and brain. In adult tissues, very abundant in ovary, high levels also observed in liver, kidney, small intestine and colon. Not detected in peripheral blood leukocytes. Detected in breast cancer cells (at protein level). {ECO:0000269|PubMed:10480909, ECO:0000269|PubMed:21871017}. |
Human Glypican 6 full length protein - ab151660 from Abcam
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GPC6 / Glypican 6 Antibody Blocking Peptide - LS-E8217 from LifeSpan Bioscience
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GPC6 / Glypican 6 Antibody Blocking Peptide - LS-E23718 from LifeSpan Bioscience
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Glypican 6 Peptide - P2033 from Novus Biologicals
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GPC6-Antibody-C-term-Blocking-peptide - BP11674b from Abgent, a WuXi AppTec company
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Glypican-6-GPC6-Antibody-N-term-Blocking-peptide - BP6374a from Abgent, a WuXi AppTec company
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Recombinant Human Glypican 6, CF - 2845-GP-050 from R&D Systems
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Human GPC6 protein - orb245853 from Biorbyt
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Human Glypican 6 protein - orb49415 from Biorbyt
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Glypican 6 protein (His tag) - 80R-3484 from Fitzgerald
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Glypican 6, Human, Recombinant - 19-C352 from ARP American Research Products
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GPC6 fusion protein - Ag17369 from Proteintech Group
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GPC6 fusion protein - ag16135 from Proteintech Group
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Recombinant Human Glypican 6 Protein - BP001413-C352 from Syd Labs
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Recombinant Human Glypican 6, His-tagged - GPC6-5629H from Creative Biomart
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Recombinant Human GPC6, His-tagged - GPC6-13417H from Creative Biomart
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Recombinant human Glypican-6 - CSB-EP009708HU CSB-BP009708HU CSB-MP009708HU from Cusabio
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Recombinant human Glypican-6 - CSB-YP009708HU from Cusabio
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Recombinant Human Glypican-6(GPC6) - CSB-YP897304HU CSB-EP897304HU CSB-BP897304HU CSB-MP897304HU from Cusabio
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Recombinant Human Glypican 6 Protein, CF - 2845-GP from R&D Systems
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GPC6 Protein - abx163378 from Abbexa
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Glypican-6 / GPC6 - TP720305 from Acris Antibodies
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Glypican 6 Recombinant Protein Antigen - NBP1-87565PEP from Novus Biologicals
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GPC6 Peptide, Human - M34GP06488H from Creative Peptides
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GPC6 Recombinant Protein (OPCA02672) - OPCA02672 from Aviva Systems Biology
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