GPC6

Gene Symbol GPC6
Entrez Gene 10082
Alt Symbol OMIMD1
Species Human
Gene Type protein-coding
Description glypican 6
Other Description glypican proteoglycan 6|glypican-6
Swissprots Q96SG5 A8K279 Q9H1P4 Q9Y625 Q96SG8
Accessions EAX08931 EAX08932 EAX08933 EAX08934 Q9Y625 AF105267 AAD55749 AF111178 AAD31392 AK074741 AK130013 AK290144 BAF82833 AK304338 BAG65183 AY358462 AAQ88827 BC106947 AAI06948 BQ009005 BQ182216 BX640888 XM_011521044 XP_011519346 NM_005708 NP_005699
Function Cell surface proteoglycan that bears heparan sulfate. Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases (By similarity). Enhances migration and invasion of cancer cells through WNT5A signaling. {ECO:0000250, ECO:0000269|PubMed:21871017}.
Subcellular Location Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}; Extracellular side {ECO:0000250}.
Tissue Specificity Widely expressed. High expression in fetal kidney and lung and lower expressions in fetal liver and brain. In adult tissues, very abundant in ovary, high levels also observed in liver, kidney, small intestine and colon. Not detected in peripheral blood leukocytes. Detected in breast cancer cells (at protein level). {ECO:0000269|PubMed:10480909, ECO:0000269|PubMed:21871017}.

glypican-6 (P-16) - sc-84281 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

glypican-6 (H-58) - sc-366377 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
glypican-6 (H-58): sc-366377. Western blot analysis of glypican-6 expression in K-562 (A) and HEK293 (B) whole cell lysates.

glypican-6 (T-20) - sc-84282 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

glypican-6 (X-24) - sc-130770 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
glypican-6 (X-24): sc-130770. Western blot analysis of glypican-6 expression in K-562 whole cell lysate.

Anti-Glypican 6 antibody - ab170523 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human kidney tissue, labeling Glypican 6 using ab170523 at a 1/50 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.

Anti-Glypican 6 antibody - ab71343 from Abcam

Prices $304.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Glypican 6 antibody (ab71343) at 1/60 dilution + K562 cell line lysate at 35 µg

Anti-Glypican 6 antibody - N-terminal - ab136295 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Glypican 6 antibody - N-terminal (ab136295) at 1 µg/ml + THP1 cell lysate at 10 µg

Anti-GPC6 / Glypican 6 Antibody - LS-C150202 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-GPC6 / Glypican 6 Antibody (aa24-527) - LS-C36518 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-GPC6 / Glypican 6 Antibody (aa36-85) - LS-C169759 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-GPC6 / Glypican 6 Antibody (aa16-46) IHC-plus™ - LS-B10702 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-GPC6 / Glypican 6 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10702 dilution 1:75.

Glypican 6 Antibody (348701) - MAB2845 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 348701

Glypican 6 Antibody [Unconjugated] - AF2845 from Novus Biologicals

Prices $99.00, $329.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

Glypican 6 Antibody - NBP1-87565 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Glypican 6 Antibody [NBP1-87565] - Glypican-6 Antibody [NBP1-87565] - Staining of human cell line A-431 shows positivity in golgi apparatus & vesicles.

Glypican 6 Polyclonal Antibody - bs-2177R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-Glypican 6 Polyclonal Antibody, Unconjugated (bs-2177R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

ANTI-GPC6 (C-TERM) antibody produced in rabbit - SAB1303579 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>GPC6 (C-term): <B>Cat. No. SAB1303579</B>: GPC6 in Human kidney tissue with GPC6 antibody (C-term) at 12.5 μg/mL.

Anti-GPC6 antibody produced in rabbit - HPA017671 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GPC6: <B>Cat. No. HPA017671</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon shows strong positivity in granular pattern in glandular cells.

GPC6 Antibody - N-terminal region (ARP65124_P050) - ARP65124_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GPC6-Antibody-C-term - AP11674b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of GPC6 (arrow) using rabbit polyclonal GPC6 Antibody (C-term) (Cat. #AP11674b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GPC6 gene.

GPC6 Antibody - N-terminal region (OAAB03469) - OAAB03469 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Glypican-6-GPC6-Antibody-N-term - AP6374a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of anti-GPC6 Pab (Cat.#AP6374a) in K562 cell line lysates (35ug/lane). GPC6(arrow) was detected using the purified Pab.

Glypican 6 / GPC6 antibody, N-term - GTX81897 from GeneTex

Prices $319.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-Glypican 6 / GPC6 antibody, N-term used in Western blot. GTX81897

GPC6 Antibody - C-terminal region (OAAB07919) - OAAB07919 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Human Glypican 6 Antibody - MAB2845 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 348701
Detection of Glypican 6 in HepG2 Human Cell Line by Flow Cytometry. HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human Glypican 6 Monoclonal Antibody (Catalog # MAB2845, filled histogram) or isotype control antibody (Catalog # MAB002 , open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B ). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004 ) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005 ). View our protocol for Staining Intracellular Molecules .

Human Glypican 6 MAb (Clone 348701), Mouse IgG1 - MAB2845-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 348701
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