Gene Symbol | CLEC9A |
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Entrez Gene | 283420 |
Alt Symbol | DNGR1, UNQ9341 |
Species | Human |
Gene Type | protein-coding |
Description | C-type lectin domain family 9, member A |
Other Description | C-type lectin domain family 9 member A|HEEE9341 |
Swissprots | B0ZBM2 Q6UXN8 |
Accessions | Q6UXN8 AK307335 AY358265 AAQ88632 DB090462 DB526089 EU339276 ABZ04557 NM_207345 NP_997228 |
Function | Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. {ECO:0000269|PubMed:18497879, ECO:0000269|PubMed:22483802}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:18408006}; Single-pass type II membrane protein {ECO:0000269|PubMed:18408006}. |
Tissue Specificity | In peripheral blood highly restricted on the surface of BDCA31(+) dendritic cells and on a small subset of CD14(+) and CD16(-) monocytes. {ECO:0000269|PubMed:18408006, ECO:0000269|PubMed:18497879}. |
CLEC-9A (E-12) - sc-167492 from Santa Cruz Biotechnology
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CLEC-9A (N-14) - sc-167494 from Santa Cruz Biotechnology
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CLEC-9A (W-12) - sc-167496 from Santa Cruz Biotechnology
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Anti-CLEC9A antibody - ab79661 from Abcam
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Anti-CLEC9A antibody - ab69364 from Abcam
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Anti-CLEC9A antibody - ab173677 from Abcam
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Anti-CLEC9A antibody [8F9] - ab104910 from Abcam
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Anti-CLEC9A antibody [IMG14N8D7] - ab172728 from Abcam
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Anti-CLEC9A antibody [MM0621-30L2] - ab135195 from Abcam
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Anti-CLEC9A Antibody (aa57-264, clone 12K64, APC) - LS-C182815 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (aa57-241, clone 12K62, APC) - LS-C182814 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (aa57-264, clone 12K64, PerCP) - LS-C182816 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (aa57-264, clone 12K64, PE) - LS-C182817 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (aa57-241) - LS-C182818 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (aa57-264, clone 11n48) - LS-C184206 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (clone 1D4B) - LS-C189793 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (aa145-173, AP) - LS-C233955 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (aa145-173, APC) - LS-C233956 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (aa145-173) - LS-C159368 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (aa145-173, Biotin) - LS-C233957 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (aa145-173, FITC) - LS-C233958 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (aa145-173, PE) - LS-C233960 from LifeSpan Bioscience
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Anti-CLEC9A Antibody (aa145-173, Azide-free, HRP) - LS-C249696 from LifeSpan Bioscience
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Anti-CLEC9A Antibody - LS-C306992 from LifeSpan Bioscience
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Anti-CLEC9A Antibody - LS-C309928 from LifeSpan Bioscience
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