Gene Symbol | CLEC9A |
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Entrez Gene | 283420 |
Alt Symbol | DNGR1, UNQ9341 |
Species | Human |
Gene Type | protein-coding |
Description | C-type lectin domain family 9, member A |
Other Description | C-type lectin domain family 9 member A|HEEE9341 |
Swissprots | B0ZBM2 Q6UXN8 |
Accessions | Q6UXN8 AK307335 AY358265 AAQ88632 DB090462 DB526089 EU339276 ABZ04557 NM_207345 NP_997228 |
Function | Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. {ECO:0000269|PubMed:18497879, ECO:0000269|PubMed:22483802}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:18408006}; Single-pass type II membrane protein {ECO:0000269|PubMed:18408006}. |
Tissue Specificity | In peripheral blood highly restricted on the surface of BDCA31(+) dendritic cells and on a small subset of CD14(+) and CD16(-) monocytes. {ECO:0000269|PubMed:18408006, ECO:0000269|PubMed:18497879}. |
Human CLEC9A full length protein - ab132795 from Abcam
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Human CLEC9A peptide - ab92420 from Abcam
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Human CLEC9A protein fragment - ab125991 from Abcam
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CLEC9a Recombinant Protein - H00283420-P01 from Novus Biologicals
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CLEC9A-Antibody-Center-Blocking-Peptide - BP17684c from Abgent, a WuXi AppTec company
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Recombinant Human CLEC9a Fc Chimera, CF - 6049-CL-050 from R&D Systems
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CLEC9A - H00283420-P01-10 from Acris Antibodies
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CLEC9A - H00283420-P01-25 from Acris Antibodies
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Recombinant Human C-type lectin domain family 9 member A(CLEC9A) - CSB-YP740922HU CSB-EP740922HU CSB-BP740922HU CSB-MP740922HU from Cusabio
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Recombinant Human CLEC9a Fc Chimera Protein, CF - 6049-CL from R&D Systems
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C-type lectin domain family 9 member A (CLEC9A), Recombinant Protein - MBS1394378 from MyBioSource
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CLEC9A Peptide, Human - M34GP03277H from Creative Peptides
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CLEC9A, Recombinant Protein - MBS635830 from MyBioSource
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Recombinant Human CLEC9a Fc Chimera Protein, CF - 6049-CL from Novus Biologicals
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Recombinant Mouse CLEC9a Fc Chimera Protein, CF - 6776-CL from Novus Biologicals
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