Gene Symbol | RHEBL1 |
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Entrez Gene | 121268 |
Alt Symbol | RHEBL1c |
Species | Human |
Gene Type | protein-coding |
Description | Ras homolog enriched in brain like 1 |
Other Description | GTPase RhebL1|Ras homolog enriched in brain like 1 c|ras homolog enriched in brain like-1 c|ras homolog enriched in brain-like protein 1|rheb-like protein 1|rheb2 |
Swissprots | Q8TAI7 Q56VH8 |
Accessions | CCQ43838 EAW58037 EAW58038 Q8TAI7 AI917432 AK098663 BAC05370 AY327412 AAP92804 AY509932 AAS80166 BC014155 AAH14155 BC027482 AAH27482 NM_001303126 NP_001290055 NM_144593 NP_653194 NR_130123 |
Function | Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2. {ECO:0000269|PubMed:12869548, ECO:0000269|PubMed:16098514, ECO:0000269|PubMed:16328882, ECO:0000269|PubMed:17162089}. |
Subcellular Location | Endomembrane system {ECO:0000305|PubMed:16328882}; Lipid-anchor {ECO:0000305|PubMed:16006564}; Cytoplasmic side {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:16328882}. |
Tissue Specificity | Ubiquitously expressed. Expression increased at least 2-fold in several tumor cell lines. {ECO:0000269|PubMed:16006564, ECO:0000269|PubMed:16328882}. |
RhebL1 (F-5) - sc-514095 from Santa Cruz Biotechnology
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RhebL1 (C-14) - sc-161185 from Santa Cruz Biotechnology
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RhebL1 (H-40) - sc-382863 from Santa Cruz Biotechnology
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RhebL1 (T-13) - sc-161187 from Santa Cruz Biotechnology
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Anti-RHEBL1 antibody - ab57333 from Abcam
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Anti-RHEBL1 antibody - N-terminal - ab170738 from Abcam
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Anti-RHEBL1 Antibody (aa17-45, AP) - LS-C239961 from LifeSpan Bioscience
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Anti-RHEBL1 Antibody (aa17-45, APC) - LS-C239963 from LifeSpan Bioscience
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Anti-RHEBL1 Antibody (aa27-76) - LS-C135286 from LifeSpan Bioscience
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Anti-RHEBL1 Antibody (aa17-45, Biotin) - LS-C239964 from LifeSpan Bioscience
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Anti-RHEBL1 Antibody (aa17-45, FITC) - LS-C239965 from LifeSpan Bioscience
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Anti-RHEBL1 Antibody (aa110-159) - LS-C82712 from LifeSpan Bioscience
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Anti-RHEBL1 Antibody (aa17-45, PE) - LS-C239966 from LifeSpan Bioscience
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Anti-RHEBL1 Antibody (aa17-45, Azide-free, HRP) - LS-C247993 from LifeSpan Bioscience
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Anti-RHEBL1 Antibody (aa24-53) - LS-C324660 from LifeSpan Bioscience
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Anti-RHEBL1 Antibody (aa17-45) - LS-C162589 from LifeSpan Bioscience
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RHEBL1 Antibody - NBP2-33674 from Novus Biologicals
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RHEBL1 Antibody - NBP2-32581 from Novus Biologicals
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RHEBL1 Antibody - NBP1-58891 from Novus Biologicals
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RHEBL1 Antibody (4G6) - H00121268-M01 from Novus Biologicals
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RHEBL1 Antibody - H00121268-B01 from Novus Biologicals
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RHEBL1 Antibody - H00121268-D01P from Novus Biologicals
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Anti-RHEBL1 antibody produced in rabbit - HPA061001 from Sigma-Aldrich
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Anti-RHEBL1 antibody produced in rabbit - SAB1410214 from Sigma-Aldrich
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Anti-RHEBL1 antibody produced in rabbit - HPA053111 from Sigma-Aldrich
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