Gene Symbol | RHEBL1 |
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Entrez Gene | 121268 |
Alt Symbol | RHEBL1c |
Species | Human |
Gene Type | protein-coding |
Description | Ras homolog enriched in brain like 1 |
Other Description | GTPase RhebL1|Ras homolog enriched in brain like 1 c|ras homolog enriched in brain like-1 c|ras homolog enriched in brain-like protein 1|rheb-like protein 1|rheb2 |
Swissprots | Q8TAI7 Q56VH8 |
Accessions | CCQ43838 EAW58037 EAW58038 Q8TAI7 AI917432 AK098663 BAC05370 AY327412 AAP92804 AY509932 AAS80166 BC014155 AAH14155 BC027482 AAH27482 NM_001303126 NP_001290055 NM_144593 NP_653194 NR_130123 |
Function | Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2. {ECO:0000269|PubMed:12869548, ECO:0000269|PubMed:16098514, ECO:0000269|PubMed:16328882, ECO:0000269|PubMed:17162089}. |
Subcellular Location | Endomembrane system {ECO:0000305|PubMed:16328882}; Lipid-anchor {ECO:0000305|PubMed:16006564}; Cytoplasmic side {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:16328882}. |
Tissue Specificity | Ubiquitously expressed. Expression increased at least 2-fold in several tumor cell lines. {ECO:0000269|PubMed:16006564, ECO:0000269|PubMed:16328882}. |
Human RHEBL1 full length protein - ab165171 from Abcam
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Human RHEBL1 protein fragment - ab165172 from Abcam
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RHEBL1 Antibody Blocking Peptide - LS-E1951 from LifeSpan Bioscience
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RHEBL1 Antibody Blocking Peptide - LS-E18972 from LifeSpan Bioscience
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RHEBL1 Antibody Blocking Peptide - LS-E18971 from LifeSpan Bioscience
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Recombinant Human RHEBL1 Protein - H00121268-P01 from Novus Biologicals
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RHEBL1 Partial Recombinant Protein - H00121268-Q01 from Novus Biologicals
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RHEBL1-Antibody-N-term-Blocking-peptide - BP12804a from Abgent, a WuXi AppTec company
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RHEBL1 Blocking Peptide - 33R-9273 from Fitzgerald
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Rhebl1 Blocking Peptide - 33R-9495 from Fitzgerald
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RHEBL1 - H00121268-P01-10 from Acris Antibodies
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RHEBL1 - H00121268-P01-25 from Acris Antibodies
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RHEBL1 - H00121268-Q01-10 from Acris Antibodies
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RHEBL1 - H00121268-Q01-25 from Acris Antibodies
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RHEBL1 fusion protein - ag4286 from Proteintech Group
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Recombinant Human GTPase RhebL1(RHEBL1) - CSB-YP855034HU CSB-EP855034HU CSB-BP855034HU CSB-MP855034HU from Cusabio
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RHEBL1 Recombinant Protein Antigen - NBP2-33674PEP from Novus Biologicals
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RHEBL1 Recombinant Protein Antigen - NBP2-32581PEP from Novus Biologicals
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RHEBL1 Peptide, Human - M34GP13269H from Creative Peptides
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GTPase RhebL1 (RHEBL1), Recombinant Protein - MBS1359094 from MyBioSource
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