ARL3

Gene Symbol ARL3
Entrez Gene 403
Alt Symbol ARFL3
Species Human
Gene Type protein-coding
Description ADP-ribosylation factor-like 3
Other Description ADP-ribosylation factor-like protein 3|ARF-like 3
Swissprots Q53X83 Q5JSM2 P36405 B2R6C7
Accessions EAW49678 P36405 AA325516 AF038193 AF493889 AAM12603 AK312525 BAG35424 AW269939 BC008032 BC009841 AAH09841 BC025759 BE780186 BM661686 BQ638232 CD245572 CR407637 CAG28565 DQ893231 ABM84157 DQ896560 ABM87559 U07151 AAA21654 NM_004311 NP_004302
Function Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase- activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit. {ECO:0000269|PubMed:16525022, ECO:0000269|PubMed:18588884, ECO:0000269|PubMed:22085962}.
Subcellular Location Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cell projection, cilium. Note=Detected predominantly in the photoreceptor connecting cilium. Present on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules.
Tissue Specificity Expressed in the retina. Strongly expressed in connecting cilium, the myoid region of the inner segments (IS) and in cone photoreceptors (at protein level). {ECO:0000269|PubMed:12417528}.

ARL3 (K-16) - sc-66331 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ARL3 (F-16) - sc-66330 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ARL3 antibody - ab154344 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ARL3 antibody (ab154344) at 1/1000 dilution + Mouse brain whole cell lysate at 50 µg

Anti-ARL3 antibody - ab38860 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Formalin fixed and paraffin embedded human breast carcinoma tissue stained with ab38860, followed by AEC staining. ab38860 at a 1/50 dilution.

Anti-ARL3 antibody - ab166854 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ARL3 antibody (ab166854) at 1/100 dilution + A2058 cell lysate at 35 µg

Anti-ARL3 antibody - ab167385 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-ARL3 antibody (ab167385) at 1 µg/mlLane 1 : ARL3 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

Anti-Arl3 antibody [3A10] - ab180482 from Abcam

Prices $357.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A10
All lanes : Anti-Arl3 antibody [3A10] (ab180482) at 1/2000 dilutionLane 1 : Lysate from HEK293T cells transfected with pCMV6-ENTRY controlLane 2 : Lysate from HEK293T cells transfected with pCMV6-ENTRY Arl3 cDNALysates/proteins at 5 µg per lane.

Anti-ARFL3 / ARL3 Antibody - LS-C334757 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of HeLa cell line, using ARL3 antibody.

Anti-ARFL3 / ARL3 Antibody (aa144-173) IHC-plus™ - LS-B8497 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ARFL3 / ARL3 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8497 dilution 5-7.5 ug/ml.

Anti-ARFL3 / ARL3 Antibody (aa2-182, clone 3E1) - LS-C336784 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ARL3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ARL3.

Anti-ARFL3 / ARL3 Antibody (aa2-182, clone 5E6) - LS-C336786 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5E6
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ARL3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ARL3.

Anti-ARFL3 / ARL3 Antibody (aa2-182, clone 7E5) - LS-C338646 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7E5
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ARL3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ARL3.

Anti-ARFL3 / ARL3 Antibody (aa2-182, clone 3A10) - LS-C336782 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A10
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ARL3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ARL3.

Anti-ARFL3 / ARL3 Antibody (aa2-182, clone 3C6) - LS-C336789 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3C6
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ARL3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ARL3.

Anti-ARFL3 / ARL3 Antibody (aa2-182, clone 2A9) - LS-C336788 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A9
IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-ARL3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-ARFL3 / ARL3 Antibody (aa2-182, clone 3D3) - LS-C338664 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3D3
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ARL3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ARL3.

Anti-ARFL3 / ARL3 Antibody (aa2-182, clone 2G7) - LS-C336785 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2G7
IHC of paraffin-embedded Human thyroid tissue using anti-ARL3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-ARFL3 / ARL3 Antibody (aa2-182, clone 1C6) - LS-C336783 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C6
IHC of paraffin-embedded Human tonsil using anti-ARL3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-ARFL3 / ARL3 Antibody (C-Terminus, AP) - LS-C275240 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARFL3 / ARL3 Antibody (aa71-120) - LS-C135578 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ARL3 antibody LS-C135578 Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.

Anti-ARFL3 / ARL3 Antibody (C-Terminus, APC) - LS-C275241 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARFL3 / ARL3 Antibody (C-Terminus, Biotin) - LS-C275242 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARFL3 / ARL3 Antibody (aa1-30) - LS-C99659 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-hARL3 -M1 antibody in A2058 cell line lysate (35 ug/lane). hARL3 -M1(arrow) was detected using the purified antibody.

Anti-ARFL3 / ARL3 Antibody (C-Terminus, FITC) - LS-C275243 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARFL3 / ARL3 Antibody (C-Terminus, Azide-free, HRP) - LS-C275244 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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