ARL3

Gene Symbol ARL3
Entrez Gene 403
Alt Symbol ARFL3
Species Human
Gene Type protein-coding
Description ADP-ribosylation factor-like 3
Other Description ADP-ribosylation factor-like protein 3|ARF-like 3
Swissprots Q53X83 Q5JSM2 P36405 B2R6C7
Accessions EAW49678 P36405 AA325516 AF038193 AF493889 AAM12603 AK312525 BAG35424 AW269939 BC008032 BC009841 AAH09841 BC025759 BE780186 BM661686 BQ638232 CD245572 CR407637 CAG28565 DQ893231 ABM84157 DQ896560 ABM87559 U07151 AAA21654 NM_004311 NP_004302
Function Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase- activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit. {ECO:0000269|PubMed:16525022, ECO:0000269|PubMed:18588884, ECO:0000269|PubMed:22085962}.
Subcellular Location Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cell projection, cilium. Note=Detected predominantly in the photoreceptor connecting cilium. Present on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules.
Tissue Specificity Expressed in the retina. Strongly expressed in connecting cilium, the myoid region of the inner segments (IS) and in cone photoreceptors (at protein level). {ECO:0000269|PubMed:12417528}.

Human ARL3 (mutated Q71 L) full length protein - ab176678 from Abcam

Category Protein
Prices $270.00
Sizes 25 µg
Source E. coli
Species Human
SDS-PAGE analysis of ab176678 stained with Coomassie Brilliant Blue.

Human ARL3 full length protein - ab113590 from Abcam

Category Protein
Prices $297.00
Sizes 100 µg
Source E. coli
Species Human
15% SDS-PAGE analysis of ab113590 (3µg)

Human ARL3 full length protein - ab176676 from Abcam

Category Protein
Prices $239.00
Sizes 100 µg
Source E. coli
Species Human
SDS-PAGE analysis of ab176676 stained with Coomassie Brilliant Blue.

ARFL3 / ARL3 Antibody Blocking Peptide - LS-E21827 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ARFL3 / ARL3 Antibody Blocking Peptide - LS-E6937 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ARFL3 / ARL3 Antibody Blocking Peptide - LS-E6938 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ARL3 Recombinant Protein - H00000403-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Species Human

Recombinant Human ARL3 Protein - NBP1-72464 from Novus Biologicals

Category Protein
Prices $269.00, $729.00
Sizes 100 µg, 500 µg
Source E. coli
Species Human

ARL3 Peptide - P1039 from Novus Biologicals

Category Peptide
Species Human

ARL3 Peptide - P1038 from Novus Biologicals

Category Peptide
Species Human

ARL3-Antibody-C-term-Blocking-Peptide - BP2306b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

ARL3-Antibody-N-term-Blocking-Peptide - BP2306a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Human ARL3 protein - orb167919 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 20 μg
Species Human

ARL3 Blocking Peptide - 33R-7712 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

ARL3 protein (His tag) - 80R-1978 from Fitzgerald

Category Protein
Prices $270.00
Sizes 100 µg
Source E.coli

ARL3 (1-182, His-tag) - AR50047PU-N from Acris Antibodies

Category Protein
Prices $790.00
Sizes 500 µg
Source E. coli
Species Human
ARL3

ARL3 (1-182, His-tag) - AR50047PU-S from Acris Antibodies

Category Protein
Prices $340.00
Sizes 100 µg
Source E. coli
Species Human
ARL3

ARL3 - H00000403-P01-02 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Source in vitro transl.
Species Human

ADP-Ribosylation Factor-Like 3, Human Recombinant - 228-13378-1 from RayBiotech

Category Protein
Prices $118.00
Sizes 1 µg
Species Human

Recombinant Human ADP-Ribosylation Factor-Like 3 - 228-13378-2 from RayBiotech

Category Protein
Prices $189.00
Sizes 2 µg
Source Escherichia Coli.
Species Human

Recombinant Human ADP-Ribosylation Factor-Like 3 - 228-13378-3 from RayBiotech

Category Protein
Prices $2,880.00
Sizes 3 µg
Source Escherichia Coli.
Species Human

ARL3, 1-182aa, Human, His tag, E.coli - 01-1904-3 from ARP American Research Products

Category Protein
Prices $179.00, $369.00, $849.00
Sizes 20 µg, 100 µg, 500 µg
Species Human

ARL3 fusion protein - Ag1406 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

ARL3 Human - PRPS-946 from NeoScientific

Category Protein
Prices $65.00, $169.00, $3,510.00
Sizes 5 µg, 20 µg, 1 mg
Source Escherichia Coli.
Species Human

Recombinant Human ADP-Ribosylation Factor-Like 3 Protein - BP001812-PRO-939 from Syd Labs

Category Protein
Prices $160.00, $2,700.00
Sizes 20 µg, 1 mg
Source E. coli-derived.
Species Human
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