LSM6

Gene Symbol LSM6
Entrez Gene 11157
Alt Symbol YDR378C
Species Human
Gene Type protein-coding
Description LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Other Description Sm protein F|U6 snRNA-associated Sm-like protein LSm6
Swissprots P62312 Q4W5J5
Accessions AAY41032 EAX05029 EAX05030 EAX05031 P62312 AF182292 AAD56230 AI351504 AJ238098 CAB45869 AK312126 BAG35062 BC016026 AAH16026 BC019894 DB465201 DQ892328 ABM83254 EU176507 ABW03308 NM_007080 NP_009011
Function Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12515382}. Nucleus {ECO:0000250}.
Top Pathways RNA degradation, Spliceosome

Human-LSM6-cDNA-Clone - DC04252 from Abgent, a WuXi AppTec company

Prices $108.00
Sizes 10 µg
Species Human
Accession BC016026

LSM6 - MBS1271215 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC016026

Human LSM6 ORF Clone(NM_007080.2) - CDCL169272 from Creative Biomart

Species Human
Accession NM_007080.2

Human LSM6 Gene cDNA clone plasmid - HG13995-G from Sino Biological

Species Human

Human LSM6 ORF Clone (BC016026) - CDCS413063 from Creative biogene

Species Human
Accession P62312

Human LSM6 ORF clone (BC016026) - CDCB159489 from Creative biogene

Species Human

Human LSM6 Gene cDNA Clone - orb144137 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human
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