LSM6

Gene Symbol	LSM6
Entrez Gene	11157
Alt Symbol	YDR378C
Species	Human
Gene Type	protein-coding
Description	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Other Description	Sm protein F|U6 snRNA-associated Sm-like protein LSm6
Swissprots	P62312 Q4W5J5
Accessions	AAY41032 EAX05029 EAX05030 EAX05031 P62312 AF182292 AAD56230 AI351504 AJ238098 CAB45869 AK312126 BAG35062 BC016026 AAH16026 BC019894 DB465201 DQ892328 ABM83254 EU176507 ABW03308 NM_007080 NP_009011
Function	Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:12515382}. Nucleus {ECO:0000250}.
Top Pathways	RNA degradation, Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LSm6 (H-40) - sc-98326 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

LSm6 (C-20) - sc-74960 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

LSm6 (K-12) - sc-74961 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

LSm6 (S-14) - sc-74962 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-LSM6 antibody - ab56828 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-LSM6 Antibody (N-Terminus) - LS-C110557 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-LSM6 Antibody (C-Terminus) - LS-C116180 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-LSM6 Antibody - LS-C137318 from LifeSpan Bioscience Prices $255.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-LSM6 Antibody (clone 4B5-1B10) - LS-C308830 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 4B5-1B10

Anti-LSM6 Antibody (aa46-58) - LS-C155026 from LifeSpan Bioscience Prices $335.00 Sizes 100 µg Host Goat Clonality Polyclonal

LSM6 Antibody - NBP1-57318 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

LSM6 Antibody - NBP1-57519 from Novus Biologicals Prices $369.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

LSM6 Antibody - NBP1-92083 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

LSM6 Antibody (4B5-1B10) - H00011157-M01 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 4B5-1B10

Monoclonal Anti-LSM6 antibody produced in mouse - WH0011157M1 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 4B5-1B10

Anti-LSM6 antibody produced in rabbit - HPA045079 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-LSM6, (N-terminal) antibody produced in rabbit - SAB2103020 from Sigma-Aldrich Prices $347.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-LSM6 antibody produced in rabbit - SAB2105436 from Sigma-Aldrich Prices $347.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

LSM6 antibody - N-terminal region (ARP40707_P050) - ARP40707_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

LSM6 antibody - middle region (ARP40708_P050) - ARP40708_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

LSM6-Antibody-internal-region - AF3787a from Abgent, a WuXi AppTec company Prices $325.00 Sizes 100 µg Host Goat Clonality Polyclonal

LSM6 antibody, Internal - GTX47331 from GeneTex Prices $319.00 Sizes 50 μg Host Rabbit Clonality Polyclonal

LSM6 antibody, N-term - GTX47332 from GeneTex Prices $319.00 Sizes 50 μg Host Rabbit Clonality Polyclonal

LSM6 antibody - orb77604 from Biorbyt Prices $425.00 Sizes 100 μg Host Rabbit Clonality Polyclonal

Goat anti-LSM6 middle region Antibody (OAEB02977) - OAEB02977 from Aviva Systems Biology Prices $229.00 Sizes 100 µg Host Goat Clonality Polyclonal

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