BCAR3

Gene Symbol BCAR3
Entrez Gene 8412
Alt Symbol NSP2, SH2D3B
Species Human
Gene Type protein-coding
Description breast cancer anti-estrogen resistance 3
Other Description SH2 domain-containing protein 3B|breast cancer anti-estrogen resistance protein 3|breast cancer antiestrogen resistance 3 protein|dJ1033H22.2 (breast cancer anti-estrogen resistance 3)|novel SH2-containing protein 2
Swissprots Q5TEW3 O75815 Q9BR50 D3DT43 Q6UW40
Accessions EAW73065 EAW73066 EAW73067 EAW73068 O75815 AF124250 AAD28245 AK027785 BAG51378 AK055442 BAG51518 AK301570 BAG63064 AK310970 AL833121 AW470748 AY358996 AAQ89355 BC028477 BC039895 AAH39895 BQ015705 CN337133 DA057195 DA745974 EU832792 ACE87803 GQ129322 ACT64456 U92715 AAC39777 XM_011542251 XP_011540553 XM_011542252 XP_011540554 NM_001261408 NP_001248337 NM_001261409 NP_001248338 NM_001261410 NP_001248339 NM_001308251 NP_001295180 NM_003567 NP_003558
Function May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins. {ECO:0000269|PubMed:9582273}.
Tissue Specificity Ubiquitously expressed. Found in several cancer cell lines, but not in nonmalignant breast tissue. {ECO:0000269|PubMed:10187783, ECO:0000269|PubMed:9582273}.

BCAR3 (N-15) - sc-47811 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BCAR3 (N-15): sc-47811. Western blot analysis of BCAR3 expression in SK-BR-3 (A), BT-20 (B) and MCF7 (C) whole cell lysates.

BCAR3 (C-18) - sc-47810 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BCAR3 (C-18): sc-47810. Western blot analysis of BCAR3 expression in non-transfected: sc-117752 (A) and human BCAR3 transfected: sc-115467 (B) 293T whole cell lysates.

BCAR3 (H-47) - sc-135217 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

BCAR3 (N-19) - sc-47812 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-BCAR3 antibody - ab65111 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue stained with BCAR3 antibody (ab65111) at 1/50 - 1/100 dilution, with (right) and without (left) the immunising peptide.

Anti-BCAR3 antibody - ab85940 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BCAR3 antibody (ab85940) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-BCAR3 antibody - ab56347 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab56347 BCAR3 antibody at 1ug/ml.

Anti-BCAR3 Antibody (aa25-75) - LS-C288459 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BCAR3 Antibody (aa813-825) - LS-C54573 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
BCAR3 antibody (0.5 ug/ml) staining of Mouse Kidney epithelial cells lysate (15 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-BCAR3 Antibody (clone 3G4) - LS-C198558 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G4
Detection limit for recombinant GST tagged BCAR3 is approximately 0.03 ng/ml as a capture antibody.

Anti-BCAR3 Antibody IHC-plus™ - LS-B7811 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BCAR3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7811 dilution 5 ug/ml.

Anti-BCAR3 Antibody (aa785-818) - LS-C344659 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from mouse spleen tissue lysate with MOUSE Bcar3 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody.

Anti-BCAR3 Antibody (N-Terminus) - LS-C153636 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of BCAR3 in human kidney tissue with BCAR3 antibody at 20 ug/ml.

BCAR3 Antibody - NB100-87003 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BCAR3 Antibody [NB100-87003] - Detection of Human BCAR3 on HeLa whole cell lysate using NB100-87003. BCAR3 was also immunoprecipitated by another rabbit anti-BCAR3 antibody.

BCAR3 Antibody - NBP1-82523 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BCAR3 Antibody [NBP1-82523] - Analysis in human cell line PC-3.

BCAR3 Antibody - 26000002 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ELISA: BCAR3 Antibody [26000002]

BCAR3 Antibody (3G4) - H00008412-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G4
Sandwich ELISA: BCAR3 Antibody (3G4) [H00008412-M01] - Detection limit for recombinant GST tagged BCAR3 is approximately 0.03ng/ml as a capture antibody.

BCAR3 Antibody - NBP2-15550 from Novus Biologicals

Host Rabbit
Clonality Polyclonal

BCAR3 Antibody - H00008412-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-BCAR3 (C-terminal) antibody produced in goat - SAB2501127 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-BCAR3 (C-terminal): <B>Cat. No. SAB2501127</B>: (0.5 μg/mL) staining of Mouse Kidney epithelial cells lysate (15 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-BCAR3, C-Terminal antibody produced in rabbit - SAB4503324 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-BCAR3, C-Terminal: <B>Cat. No. SAB4503324</B>: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-BCAR3, C-Terminal antibody. Cells on the left were treated with the Anti-BCAR3, C-Terminal antibody. Cells on the right (negative control) were treated with both Anti-BCAR3, C-Terminal antibody and the synthesized immunogen peptide.

Monoclonal Anti-BCAR3 antibody produced in mouse - WH0008412M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G4
<B>Immunoblotting</B><BR/>Monoclonal Anti-BCAR3, <B>Cat. No. WH0008412M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~37.88 kDa using immunogen protein lysate.

Anti-BCAR3 antibody produced in rabbit - HPA014858 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-BCAR3: <B>Cat. No. HPA014858</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney shows moderate cytoplasmic positivity in tubular cells.

BCAR3-Antibody-monoclonal-M01 - AT1278a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G4
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.51 KDa) .

BCAR3-Antibody - AF1145a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1145a (0.5 µg/ml) staining of Mouse Kidney epithelial cells lysate (15 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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