BCAR3

Gene Symbol BCAR3
Entrez Gene 8412
Alt Symbol NSP2, SH2D3B
Species Human
Gene Type protein-coding
Description breast cancer anti-estrogen resistance 3
Other Description SH2 domain-containing protein 3B|breast cancer anti-estrogen resistance protein 3|breast cancer antiestrogen resistance 3 protein|dJ1033H22.2 (breast cancer anti-estrogen resistance 3)|novel SH2-containing protein 2
Swissprots Q5TEW3 O75815 Q9BR50 D3DT43 Q6UW40
Accessions EAW73065 EAW73066 EAW73067 EAW73068 O75815 AF124250 AAD28245 AK027785 BAG51378 AK055442 BAG51518 AK301570 BAG63064 AK310970 AL833121 AW470748 AY358996 AAQ89355 BC028477 BC039895 AAH39895 BQ015705 CN337133 DA057195 DA745974 EU832792 ACE87803 GQ129322 ACT64456 U92715 AAC39777 XM_011542251 XP_011540553 XM_011542252 XP_011540554 NM_001261408 NP_001248337 NM_001261409 NP_001248338 NM_001261410 NP_001248339 NM_001308251 NP_001295180 NM_003567 NP_003558
Function May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins. {ECO:0000269|PubMed:9582273}.
Tissue Specificity Ubiquitously expressed. Found in several cancer cell lines, but not in nonmalignant breast tissue. {ECO:0000269|PubMed:10187783, ECO:0000269|PubMed:9582273}.

BCAR3 CRISPR/Cas9 KO Plasmid (h) - sc-404301 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCAR3 HDR Plasmid (h) - sc-404301-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCAR3 Double Nickase Plasmid (h) - sc-404301-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCAR3 Double Nickase Plasmid (h2) - sc-404301-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCAR3 CRISPR Activation Plasmid (h) - sc-404301-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCAR3 CRISPR Activation Plasmid (h2) - sc-404301-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCAR3 Lentiviral Activation Particles (h) - sc-404301-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCAR3 Lentiviral Activation Particles (h2) - sc-404301-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCAR3 siRNA (h) - sc-60265 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BCAR3 shRNA Plasmid (h) - sc-60265-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BCAR3 shRNA (h) Lentiviral Particles - sc-60265-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BCAR3 RNAi - H00008412-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU060381 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3891 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04325 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04325

BCAR3 siRNA (Human) - CRH5514 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BCAR3 - MBS8206923 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BCAR3 (NM_003567.3) - SHH245694 from Creative biogene

Category siRNA
Species Reactivities Human

Human BCAR3 siRNA - orb266016 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BCAR3 shRNA Plasmid (Human) - CHH5514 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BCAR3 miRNA 3'UTR clone - MiUTR3H-07024 from Creative biogene

Species Reactivities Human
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