Nkx2-2

Gene Symbol	Nkx2-2
Entrez Gene	18088
Alt Symbol	Nkx-2.2, Nkx2.2, tinman
Species	Mouse
Gene Type	protein-coding
Description	NK2 homeobox 2
Other Description	Drosophila NK2 transcription factor related, locus 2|NK2 transcription factor related, locus 2|glycoprotein GP330, renal|homeobox protein NK-2 homolog B|homeobox protein Nkx-2.2|homeobox protein Nkx2-2
Swissprots	P42586
Accessions	AAF44652 P42586 AK043561 BAC31582 AK141002 BAE24543 AK162904 BAE37107 BB183898 BC138159 AAI38160 BC138160 AAI38161 U31566 AAA79303 XM_006498898 XP_006498961 XM_006498899 XP_006498962 XM_006498900 XP_006498963 XM_011239349 XP_011237651 NM_001077632 NP_001071100 NM_010919 NP_035049
Function	Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter. {ECO:0000269|PubMed:19759004}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:14573534}.
Tissue Specificity	Expressed in restricted areas of the developing CNS: the hindbrain and forebrain, and pancreas.
Top Pathways	Maturity onset diabetes of the young

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Recombinant Mouse Homeobox protein Nkx-2.2(Nkx2-2) - CSB-YP015842MO CSB-EP015842MO CSB-BP015842MO CSB-MP015842MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Nkx2-2 Recombinant Protein (OPCA03134) - OPCA03134 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Mouse

Mouse Nkx2-2 protein - orb358357 from Biorbyt Category Protein Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Mouse

Recombinant Mouse Homeobox protein Nkx-2.2(Nkx2-2) - AP73768 from Signalway Antibody Category Protein Prices $105.00, $260.00, $454.00, $735.00, $1,240.00, $1,980.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Mouse

Homeobox protein Nkx-2.2 , Recombinant Protein - MBS717971 from MyBioSource Category Protein Prices $110.00, $190.00, $460.00, $750.00, $1,025.00, $1,180.00, $1,255.00, $1,255.00, $1,585.00, $2,050.00, $2,050.00 Sizes 10 µg (E-Coli), 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 50 µg (Baculovirus), 1 mg (E-Coli), 500 µg (Yeast), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

Homeobox protein Nkx-2.2 (Nkx2-2), Recombinant Protein - MBS9423348 from MyBioSource Category Protein Prices $165.00, $280.00, $435.00, $665.00, $1,080.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg Source E Coli Species Mouse

Recombinant Mouse NKX2-2 Protein (1-273 aa), His-SUMO-tagged - NKX2-2-1766M from Creative Biomart Category Protein Source E. coli Species Mouse

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