Gene Symbol | GCC2 |
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Entrez Gene | 9648 |
Alt Symbol | GCC185, RANBP2L4, REN53 |
Species | Human |
Gene Type | protein-coding |
Description | GRIP and coiled-coil domain containing 2 |
Other Description | 185 kDa Golgi coiled-coil protein|CLL-associated antigen KW-11|CTCL tumor antigen se1-1|GCC protein, 185-kD|GRIP and coiled-coil domain-containing protein 2|Golgi coiled-coil protein GCC185|Ran-binding protein 2-like 4|renal carcinoma antigen NY-REN-53 |
Swissprots | Q8TDH3 Q8IWJ2 A6H8X8 O15045 Q9H2G8 Q4ZG46 |
Accessions | AAX88838 EAW53882 EAW53883 EAW53884 Q8IWJ2 AA171957 AB002334 BAA20794 AF273042 AAG34902 AF432211 AAL99918 AI084646 AK090813 BAG52233 AK308707 BC020645 AAH20645 BC037774 AAH37774 BC146789 AAI46790 BM694019 DA865539 XM_006712870 XP_006712933 XM_006712871 XP_006712934 XM_006712872 XP_006712935 XM_011512213 XP_011510515 XR_923067 XR_923068 NM_181453 NP_852118 NR_028063 |
Function | Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2. {ECO:0000269|PubMed:16885419, ECO:0000269|PubMed:17488291, ECO:0000269|PubMed:17543864}. |
Subcellular Location | Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11149944}. |
GCC2 (E-20) - sc-242898 from Santa Cruz Biotechnology
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Anti-GCC2 antibody - ab107755 from Abcam
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Anti-GCC2 antibody - ab128173 from Abcam
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Anti-GCC2 antibody - ab128151 from Abcam
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Anti-GCC2 Antibody (aa1581-1609, APC) - LS-C235569 from LifeSpan Bioscience
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Anti-GCC2 Antibody (aa1581-1609, PE) - LS-C235573 from LifeSpan Bioscience
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Anti-GCC2 Antibody (aa1581-1609, Biotin) - LS-C235570 from LifeSpan Bioscience
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Anti-GCC2 Antibody (aa50-100) - LS-C290235 from LifeSpan Bioscience
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Anti-GCC2 Antibody (aa1581-1609, FITC) - LS-C235571 from LifeSpan Bioscience
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Anti-GCC2 Antibody (aa1581-1609, Azide-free, HRP) - LS-C249044 from LifeSpan Bioscience
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Anti-GCC2 Antibody (aa1548-1617) - LS-C321576 from LifeSpan Bioscience
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Anti-GCC2 Antibody (aa1-50) - LS-C290236 from LifeSpan Bioscience
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Anti-GCC2 Antibody (aa1581-1609) - LS-C166407 from LifeSpan Bioscience
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Anti-GCC2 Antibody (aa1174-1185) IHC-plus⢠- LS-B4938 from LifeSpan Bioscience
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Anti-GCC2 Antibody (aa1581-1609, AP) - LS-C235568 from LifeSpan Bioscience
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GCC185 Antibody - NBP1-89788 from Novus Biologicals
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GCC185 Antibody - NBP1-20922 from Novus Biologicals
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GCC185 Antibody - NBP2-04024 from Novus Biologicals
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GCC185 Antibody - NBP2-38267 from Novus Biologicals
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Rabbit Anti-GCC2 Polyclonal Antibody - bs-13311R from Bioss
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Rabbit Anti-GCC2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13311R-A350 from Bioss
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Rabbit Anti-GCC2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13311R-A488 from Bioss
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Rabbit Anti-GCC2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13311R-A555 from Bioss
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Rabbit Anti-GCC2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13311R-A647 from Bioss
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Rabbit Anti-GCC2 Polyclonal Antibody, Cy3 Conjugated - bs-13311R-Cy3 from Bioss
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