Gene Symbol | GCC2 |
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Entrez Gene | 9648 |
Alt Symbol | GCC185, RANBP2L4, REN53 |
Species | Human |
Gene Type | protein-coding |
Description | GRIP and coiled-coil domain containing 2 |
Other Description | 185 kDa Golgi coiled-coil protein|CLL-associated antigen KW-11|CTCL tumor antigen se1-1|GCC protein, 185-kD|GRIP and coiled-coil domain-containing protein 2|Golgi coiled-coil protein GCC185|Ran-binding protein 2-like 4|renal carcinoma antigen NY-REN-53 |
Swissprots | Q8TDH3 Q8IWJ2 A6H8X8 O15045 Q9H2G8 Q4ZG46 |
Accessions | AAX88838 EAW53882 EAW53883 EAW53884 Q8IWJ2 AA171957 AB002334 BAA20794 AF273042 AAG34902 AF432211 AAL99918 AI084646 AK090813 BAG52233 AK308707 BC020645 AAH20645 BC037774 AAH37774 BC146789 AAI46790 BM694019 DA865539 XM_006712870 XP_006712933 XM_006712871 XP_006712934 XM_006712872 XP_006712935 XM_011512213 XP_011510515 XR_923067 XR_923068 NM_181453 NP_852118 NR_028063 |
Function | Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2. {ECO:0000269|PubMed:16885419, ECO:0000269|PubMed:17488291, ECO:0000269|PubMed:17543864}. |
Subcellular Location | Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11149944}. |
GCC2 Antibody Blocking Peptide - LS-E105 from LifeSpan Bioscience
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GCC2 Antibody Blocking Peptide - LS-E26442 from LifeSpan Bioscience
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GCC2-Antibody-C-term-Blocking-peptide - BP10197b from Abgent, a WuXi AppTec company
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GCC185 blocking peptide - GTX88740-PEP from GeneTex
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GCC2 Immunizing peptide - orb50438 from Biorbyt
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GCC2 Peptide - AC21-1281-P from Abcore
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GCC185 Peptide - 46-846P from ProSci
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GCC2 fusion protein - Ag17535 from Proteintech Group
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GCC2 fusion protein - Ag17664 from Proteintech Group
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Recombinant Human GCC2, GST-tagged - GCC2-13188H from Creative Biomart
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Recombinant Human GRIP and coiled-coil domain-containing protein 2(GCC2) ,partia - CSB-YP810280HU CSB-EP810280HU CSB-BP810280HU CSB-MP810280HU from Cusabio
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GCC185, Peptide - MBS426613 from MyBioSource
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GCC185 Recombinant Protein Antigen - NBP2-38267PEP from Novus Biologicals
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GCC185 Protein - NBP1-89788PEP from Novus Biologicals
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GCC2 Peptide, Human - M34GP06155H from Creative Peptides
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GRIP and coiled-coil domain-containing protein 2 (GCC2), partial, Recombinant Protein - MBS1437297 from MyBioSource
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