Gene Symbol | LFNG |
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Entrez Gene | 3955 |
Alt Symbol | SCDO3 |
Species | Human |
Gene Type | protein-coding |
Description | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
Other Description | beta-1,3-N-acetylglucosaminyltransferase lunatic fringe |
Swissprots | Q96C39 O00589 Q9UJW5 B5MCR5 B3KTY6 Q8NES3 |
Accessions | AAM93542 EAW87250 EAW87251 EAW87252 EAW87253 EAW87254 Q8NES3 AF193612 AAF07187 AK096284 BAG53248 BC014851 AAH14851 BM854210 U94354 AAC51360 NM_001040167 NP_001035257 NM_001040168 NP_001035258 NM_001166355 NP_001159827 NM_002304 NP_002295 |
Function | Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Other types of O-glycan biosynthesis, Notch signaling pathway |
Lunatic Fringe (TT-07) - sc-100756 from Santa Cruz Biotechnology
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Lunatic Fringe (N-16) - sc-324092 from Santa Cruz Biotechnology
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Lunatic Fringe (P-16) - sc-324094 from Santa Cruz Biotechnology
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Anti-Lunatic Fringe antibody - ab102835 from Abcam
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Anti-Lunatic Fringe antibody - ab58078 from Abcam
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Anti-Lunatic Fringe antibody [EPR10391(B)] - ab151699 from Abcam
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Anti-LFNG / Lunatic Fringe Antibody (aa86-114) IHC-plus⢠- LS-B10951 from LifeSpan Bioscience
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Anti-LFNG / Lunatic Fringe Antibody (aa93-122, FITC) - LS-C215593 from LifeSpan Bioscience
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Anti-LFNG / Lunatic Fringe Antibody (aa93-122, APC) - LS-C215592 from LifeSpan Bioscience
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Anti-LFNG / Lunatic Fringe Antibody (aa93-122, AP) - LS-C215591 from LifeSpan Bioscience
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Anti-LFNG / Lunatic Fringe Antibody (aa93-122, Biotin) - LS-C215594 from LifeSpan Bioscience
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Anti-LFNG / Lunatic Fringe Antibody (aa93-122, Azide-free, HRP) - LS-C215595 from LifeSpan Bioscience
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Anti-LFNG / Lunatic Fringe Antibody (aa93-122, PE) - LS-C215596 from LifeSpan Bioscience
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Anti-LFNG / Lunatic Fringe Antibody - LS-C310908 from LifeSpan Bioscience
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Anti-LFNG / Lunatic Fringe Antibody (aa1-251, Azide-free) - LS-C327784 from LifeSpan Bioscience
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Anti-LFNG / Lunatic Fringe Antibody (aa93-122) - LS-C329760 from LifeSpan Bioscience
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Anti-LFNG / Lunatic Fringe Antibody (aa121-170) - LS-C199198 from LifeSpan Bioscience
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Anti-LFNG / Lunatic Fringe Antibody (clone 2D10-3C11) - LS-C197612 from LifeSpan Bioscience
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Anti-LFNG / Lunatic Fringe Antibody (aa74-123) IHC-plus⢠- LS-B9718 from LifeSpan Bioscience
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Lunatic Fringe Antibody - NBP1-59432 from Novus Biologicals
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Lunatic Fringe Antibody - NBP2-39097 from Novus Biologicals
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Lunatic Fringe Antibody (1F9) - H00003955-M03 from Novus Biologicals
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Lunatic Fringe Antibody (2D10-3C11) - H00003955-M01 from Novus Biologicals
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Lunatic Fringe Antibody - H00003955-D01P from Novus Biologicals
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Lunatic Fringe Antibody (3D12) - H00003955-M06 from Novus Biologicals
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