Gene Symbol | LFNG |
---|---|
Entrez Gene | 3955 |
Alt Symbol | SCDO3 |
Species | Human |
Gene Type | protein-coding |
Description | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
Other Description | beta-1,3-N-acetylglucosaminyltransferase lunatic fringe |
Swissprots | Q96C39 O00589 Q9UJW5 B5MCR5 B3KTY6 Q8NES3 |
Accessions | AAM93542 EAW87250 EAW87251 EAW87252 EAW87253 EAW87254 Q8NES3 AF193612 AAF07187 AK096284 BAG53248 BC014851 AAH14851 BM854210 U94354 AAC51360 NM_001040167 NP_001035257 NM_001040168 NP_001035258 NM_001166355 NP_001159827 NM_002304 NP_002295 |
Function | Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Other types of O-glycan biosynthesis, Notch signaling pathway |
Human Lunatic Fringe full length protein - ab116899 from Abcam
|
||||||||||
LFNG / Lunatic Fringe Antibody Blocking Peptide - LS-E10176 from LifeSpan Bioscience
|
||||||||||
Recombinant Human Lunatic Fringe Protein - H00003955-P01 from Novus Biologicals
|
||||||||||
LFNG-Antibody-Center-Blocking-Peptide - BP9524c from Abgent, a WuXi AppTec company
|
||||||||||
LFNG Blocking Peptide - 33R-5423 from Fitzgerald
|
||||||||||
LFNG - H00003955-P01-10 from Acris Antibodies
|
||||||||||
LFNG - H00003955-P01-25 from Acris Antibodies
|
||||||||||
LFNG fusion protein - ag10804 from Proteintech Group
|
||||||||||
Recombinant Human LFNG - LFNG-29854TH from Creative Biomart
|
||||||||||
Recombinant Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe(LFNG) - CSB-YP839868HU CSB-EP839868HU CSB-BP839868HU CSB-MP839868HU from Cusabio
|
||||||||||
LFNG Protein - abx164052 from Abbexa
|
||||||||||
Lunatic Fringe Recombinant Protein Antigen - NBP2-39097PEP from Novus Biologicals
|
||||||||||
LFNG Peptide, Human - M34GP08652H from Creative Peptides
|
||||||||||
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (LFNG), Recombinant Protein - MBS1365900 from MyBioSource
|
||||||||||
LFNG Recombinant Protein (Human) (OPCA04967) - OPCA04967 from Aviva Systems Biology
|
||||||||||
Recombinant Human LFNG Protein (1-250 aa), GST-tagged - LFNG-2140H from Creative Biomart
|