Gene Symbol | SPAG1 |
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Entrez Gene | 6674 |
Alt Symbol | CILD28, CT140, HSD-3.8, SP75, TPIS |
Species | Human |
Gene Type | protein-coding |
Description | sperm associated antigen 1 |
Other Description | TPR-containing protein involved in spermatogenesis|infertility-related sperm protein Spag-1|sperm-associated antigen 1|tetratricopeptide repeat-containing protein |
Swissprots | A6NP70 Q07617 B3KQ58 Q7Z5G1 G3XAM3 |
Accessions | EAW91800 EAW91801 EAW91802 EAW91803 EAW91804 EAW91805 EAW91806 Q07617 AF311312 AAG23967 AI624411 AK057482 BAG51920 BC055091 AAH55091 BM557203 BM981630 BX480304 DB028984 XM_011517240 XP_011515542 XM_011517241 XP_011515543 XM_011517242 XP_011515544 XM_011517243 XP_011515545 XM_011517244 XP_011515546 XM_011517245 XP_011515547 NM_003114 NP_003105 NM_172218 NP_757367 |
Function | May play a role in the cytoplasmic assembly of the ciliary dynein arms (By similarity). May play a role in fertilization. Binds GTP and has GTPase activity. {ECO:0000250, ECO:0000269|PubMed:11517287, ECO:0000269|PubMed:1299558}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11517287, ECO:0000269|PubMed:16983343}. Note=Colocalizes with tubulin. |
Tissue Specificity | Present in most tissues, including lung, with the strongest expression in brain, colon, kidney, and testis. In sperm and testis, detected in particular in pachytene primary spermatocytes. Up-regulated in pancreatic tumor tissues and not in normal pancreatic tissue. {ECO:0000269|PubMed:11517287, ECO:0000269|PubMed:1299558, ECO:0000269|PubMed:16983343, ECO:0000269|PubMed:24055112}. |
SPAG1 (S-17) - sc-98146 from Santa Cruz Biotechnology
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Anti-spag1 antibody - ab183089 from Abcam
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Anti-spag1 antibody - ab133902 from Abcam
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Anti-spag1 antibody - N-terminal - ab168833 from Abcam
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Anti-SPAG1 / TPIS Antibody (aa124-152) - LS-C161421 from LifeSpan Bioscience
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Anti-SPAG1 / TPIS Antibody (N-Terminus, AP) - LS-C217682 from LifeSpan Bioscience
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Anti-SPAG1 / TPIS Antibody (N-Terminus, APC) - LS-C217683 from LifeSpan Bioscience
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Anti-SPAG1 / TPIS Antibody (N-Terminus, Biotin) - LS-C217684 from LifeSpan Bioscience
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Anti-SPAG1 / TPIS Antibody (N-Terminus, FITC) - LS-C217685 from LifeSpan Bioscience
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Anti-SPAG1 / TPIS Antibody (N-Terminus, Azide-free, HRP) - LS-C217686 from LifeSpan Bioscience
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Anti-SPAG1 / TPIS Antibody (N-Terminus, PE) - LS-C217687 from LifeSpan Bioscience
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Anti-SPAG1 / TPIS Antibody (N-Terminus) - LS-C325304 from LifeSpan Bioscience
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Anti-SPAG1 / TPIS Antibody (aa755-804) - LS-C152050 from LifeSpan Bioscience
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Anti-SPAG1 / TPIS Antibody (aa138-187) - LS-C186778 from LifeSpan Bioscience
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SPAG1 Antibody - NBP2-38707 from Novus Biologicals
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SPAG1 Antibody - H00006674-A01 from Novus Biologicals
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Anti-SPAG1 antibody produced in rabbit - HPA023748 from Sigma-Aldrich
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SPAG1 Antibody - N-terminal region (ARP65711_P050) - ARP65711_P050 from Aviva Systems Biology
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SPAG1 Antibody - C-terminal region (ARP65712_P050) - ARP65712_P050 from Aviva Systems Biology
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SPAG1 Antibody - N-terminal region (OAAB03107) - OAAB03107 from Aviva Systems Biology
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SPAG1-Antibody-N-term - AP5699a from Abgent, a WuXi AppTec company
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SPAG1 antibody - H00006674-A01 from Acris Antibodies
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SPAG1 antibody - H00006674-B01P from Acris Antibodies
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Anti-SPAG1 antibody - STJ25668 from St John's Laboratory Ltd
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SPAG1-Specific antibody - 19720-1-AP from Proteintech Group
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