Gene Symbol | SPAG1 |
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Entrez Gene | 6674 |
Alt Symbol | CILD28, CT140, HSD-3.8, SP75, TPIS |
Species | Human |
Gene Type | protein-coding |
Description | sperm associated antigen 1 |
Other Description | TPR-containing protein involved in spermatogenesis|infertility-related sperm protein Spag-1|sperm-associated antigen 1|tetratricopeptide repeat-containing protein |
Swissprots | A6NP70 Q07617 B3KQ58 Q7Z5G1 G3XAM3 |
Accessions | EAW91800 EAW91801 EAW91802 EAW91803 EAW91804 EAW91805 EAW91806 Q07617 AF311312 AAG23967 AI624411 AK057482 BAG51920 BC055091 AAH55091 BM557203 BM981630 BX480304 DB028984 XM_011517240 XP_011515542 XM_011517241 XP_011515543 XM_011517242 XP_011515544 XM_011517243 XP_011515545 XM_011517244 XP_011515546 XM_011517245 XP_011515547 NM_003114 NP_003105 NM_172218 NP_757367 |
Function | May play a role in the cytoplasmic assembly of the ciliary dynein arms (By similarity). May play a role in fertilization. Binds GTP and has GTPase activity. {ECO:0000250, ECO:0000269|PubMed:11517287, ECO:0000269|PubMed:1299558}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11517287, ECO:0000269|PubMed:16983343}. Note=Colocalizes with tubulin. |
Tissue Specificity | Present in most tissues, including lung, with the strongest expression in brain, colon, kidney, and testis. In sperm and testis, detected in particular in pachytene primary spermatocytes. Up-regulated in pancreatic tumor tissues and not in normal pancreatic tissue. {ECO:0000269|PubMed:11517287, ECO:0000269|PubMed:1299558, ECO:0000269|PubMed:16983343, ECO:0000269|PubMed:24055112}. |
Human SPAG1 / TPIS ELISA Kit (Sandwich ELISA) - LS-F12647 from LifeSpan Bioscience
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Sperm-associated antigen 1, SPAG1, Human, ELISA Kit - E9879h from ARP American Research Products
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sperm associated antigen 1, ELISA Kit - MBS9332829 from MyBioSource
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Mouse SPAG1 / TPIS ELISA Kit (Custom ELISA) - LS-F20603 from LifeSpan Bioscience
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Rat SPAG1 / TPIS ELISA Kit (Custom ELISA) - LS-F20604 from LifeSpan Bioscience
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Human Sperm-associated antigen 1 ELISA Kit - abx251897 from Abbexa
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Human Sperm-associated antigen 1 ELISA Kit - EKE55470 from Biomatik
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SPAG1 - EKH5050 from Nordic BioSite
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SPAG1 ELISA Kit (Human) (OKEH02027) - OKEH02027 from Aviva Systems Biology
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Human SPAG1 ELISA Kit - E036349 from Biobool
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Human Sperm-associated antigen 1 ELISA Kit - EK5059 from Signalway Antibody
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Sperm-associated antigen 1, ELISA Kit - MBS9428885 from MyBioSource
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Sperm-associated antigen 1, ELISA Kit - MBS288946 from MyBioSource
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Sperm-associated antigen 1, ELISA Kit - MBS761048 from MyBioSource
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Human SPAG1 / TPIS ELISA Kit (Sandwich ELISA) - LS-F34017 from LifeSpan Bioscience
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